Clinic for Child and Adolescent Medicine, Sana Klinikum Lichtenberg, Academic Teaching Hospital, Charité-Universitätsmedizin, Fanningerstr. 32, 10365, Berlin, Germany.
Department of Pediatrics, University Hospital and Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Infection. 2022 Dec;50(6):1587-1590. doi: 10.1007/s15010-022-01889-6. Epub 2022 Jul 29.
Public health measures implemented to mitigate the effects of the COVID-19 pandemic disrupted the worldwide transmission of endemic respiratory viruses such as RSV, as well as other typical, seasonal, and viral respiratory pathogens.
From October 18, 2021 to March 31, 2022, RSV cases admitted to German pediatric hospitals were monitored via a newly established, national, Clinician-Led Reporting System (CLRS) that recorded patient age and type of respiratory support. A subanalysis of the first 4 months of the monitoring period was additionally performed.
In October 2021, a total of 471 hospitalized pediatric RSV cases per day were documented by 67 reporting hospitals. By January 2022, this number dropped to three cases at 11 hospitals (median of reporting hospitals: 37 (11%)). During these months, the median of hospitalized children on general wards and intensive care units was 133 and 15, respectively. In the subanalysis conducted to examine the period October to January, an average of 3.6 ± 2.2 patients per hospital per day were hospitalized on general wards (median 4 cases; range 0.3-8 cases), whereas 0.4 ± 2.2 patients were on intensive care units (median 0.3 cases; range 0-0.9 cases), with 11.5% receiving respiratory support. The majority of patients were under 2 years old.
The overall burden of out-of-season RSV cases was extraordinarily high in Germany in 2021-2022. The newly established CLRS may help evaluate and, therefore, better allocate local and national pediatric care resources.
为减轻 COVID-19 大流行的影响而实施的公共卫生措施中断了 RSV 等地方性呼吸道病毒以及其他典型的季节性和病毒性呼吸道病原体的全球传播。
从 2021 年 10 月 18 日至 2022 年 3 月 31 日，德国儿科医院通过新建立的临床医生主导的报告系统（CLRS）监测呼吸道合胞病毒（RSV）入院病例，该系统记录患者年龄和呼吸支持类型。还对监测期的前 4 个月进行了子分析。
2021 年 10 月，67 家报告医院每天记录了 471 例住院儿科 RSV 病例。到 2022 年 1 月，这一数字下降到 11 家医院的 3 例（报告医院中位数：37（11%））。在此期间，普通病房和重症监护病房住院儿童的中位数分别为 133 和 15。在对 10 月至 1 月期间进行的子分析中，每家医院平均每天有 3.6±2.2 例患者住院普通病房（中位数 4 例；范围 0.3-8 例），有 0.4±2.2 例患者入住重症监护病房（中位数 0.3 例；范围 0-0.9 例），有 11.5%接受呼吸支持。大多数患者年龄在 2 岁以下。
2021-2022 年，德国非季节性 RSV 病例的总体负担异常高。新建立的 CLRS 可能有助于评估，从而更好地分配当地和国家儿科护理资源。
