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严重骨缺损拔牙窝牙槽嵴增高的组织学和临床评估:一项临床前瞻性研究。

Histologic and Clinical Evaluation of Ridge Augmentation of Extraction Sockets with Severe Bone Defects: A Clinical Prospective Study.

出版信息

Int J Oral Maxillofac Implants. 2022 Jul-Aug;37(4):778-783. doi: 10.11607/jomi.9651.

Abstract

PURPOSE

To primarily evaluate the dimensional changes of bone and soft tissue following ridge augmentation in compromised molar regions. The secondary objective was to evaluate the histologic composition of augmented sites.

MATERIALS AND METHODS

The study included 27 patients who underwent augmentation of extraction sites with grafts covered by a collagen membrane. CBCT was taken immediately after augmentation (T2) and after 8 months of healing, before implant placement (T3). The width and height of the extraction sites were recorded at extraction (T1) and reentry surgery (T4). A histomorphometric analysis was performed. Data were evaluated in terms of bone crest level, implant survival rates, and change in mucogingival junction.

RESULTS

According to clinical measurement, horizontal and vertical bone gain was 10.15 ± 1.00 mm and 8.80 ± 1.86 mm, respectively. Radiographic measurement showed that the horizontal width changes were 1.46 ± 0.52 mm, 0.98 ± 1.29 mm, and 1.29 ± 0.82 mm, respectively, at 1, 3, and 5 mm apical to the crestal level. Vertical bone change was 2.34 ± 0.90 mm in the center of the socket. Histomorphometric analysis showed that percentages of mineralized bone, nonmineralized tissue, and bone substitute were 32.31% ± 13.25%, 25.36% ± 12.24%, and 42.34% ± 9.54%, respectively. The mucogingival junction shift was 0.6 ± 1.1 mm. Implant survival rates and crestal bone resorption were 100% and 0.78 ± 0.58 mm, respectively, after 1 year of loading.

CONCLUSION

Ridge augmentation can be performed successfully to manage extraction sockets. Membrane coverage combined with primary wound closure could be conducive to new bone regeneration and peri-implant tissue health.

摘要

目的

主要评估在受损磨牙区域进行牙槽嵴增高后骨和软组织的尺寸变化。次要目标是评估增强部位的组织学组成。

材料和方法

本研究纳入了 27 名接受使用胶原膜覆盖移植物进行牙槽嵴增高的患者。在增高后即刻(T2)和植入物放置前 8 个月的愈合期(T3)拍摄 CBCT。在拔牙(T1)和再入手术(T4)时记录拔牙部位的宽度和高度。进行组织形态计量分析。根据骨嵴水平、种植体存活率和黏骨膜联合变化评估数据。

结果

根据临床测量,水平和垂直骨增量分别为 10.15 ± 1.00 mm 和 8.80 ± 1.86 mm。放射测量显示,在嵴顶水平以上 1、3 和 5 mm 处,水平宽度的变化分别为 1.46 ± 0.52、0.98 ± 1.29 和 1.29 ± 0.82 mm。牙槽窝中心的垂直骨变化为 2.34 ± 0.90 mm。组织形态计量分析显示,矿化骨、非矿化组织和骨替代物的百分比分别为 32.31% ± 13.25%、25.36% ± 12.24%和 42.34% ± 9.54%。黏骨膜联合移位为 0.6 ± 1.1 mm。在 1 年的负重后,种植体存活率和骨嵴吸收分别为 100%和 0.78 ± 0.58 mm。

结论

牙槽嵴增高术可成功用于处理拔牙窝。膜覆盖联合一期创口关闭有助于新骨再生和种植体周围组织健康。

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