Department of Neurology, University Medicine Greifswald, Greifswald, Germany.
Department of Neurology, University Medicine Greifswald, Greifswald, Germany.
Neurosci Biobehav Rev. 2022 Sep;140:104796. doi: 10.1016/j.neubiorev.2022.104796. Epub 2022 Jul 26.
Trajectories of decline across different socio-cognitive domains in healthy older adults and in pathological aging conditions have not been investigated. This was addressed in the present systematic review and meta-analysis.
MEDLINE, Web of Science Core Collection, CENTRAL, and PsycInfo were searched for studies investigating social cognition across four domains (Theory of Mind, ToM; emotion recognition, ER; Social-decision making, SD; visual perspective taking, VPT) in healthy older individuals, individuals with subjective and mild cognitive impairment (SCD, MCI) and Alzheimer's disease (AD). Random-effects meta-analyses were conducted.
Of 8137 screened studies, 132 studies were included in the review. ToM and ER showed a clear progression of impairment from normal aging to AD. Differential patterns of decline were identified for different types of ToM and ER.
This systematic review identified progression of impairment of specific socio-cognitive abilities, which is the necessary pre-requisite for developing targeted interventions. We identified a lack of research on socio-cognitive decline in different populations (e.g., middle age, SCD and MCI-subtypes) and domains (SDM, VPT).
尚未研究健康老年人和病理性衰老情况下不同社会认知领域的衰退轨迹。本系统评价和荟萃分析对此进行了研究。
在 MEDLINE、Web of Science 核心合集、CENTRAL 和 PsycInfo 中搜索了研究健康老年人、主观认知障碍（SCD）和轻度认知障碍（MCI）以及阿尔茨海默病（AD）个体四个社会认知领域（心理理论、情绪识别、社会决策、视觉观点采择）的社会认知的研究。进行了随机效应荟萃分析。
在 8137 篇筛选的研究中，有 132 篇研究纳入了综述。心理理论和情绪识别显示出从正常衰老到 AD 的明显损伤进展。不同类型的心理理论和情绪识别表现出不同的衰退模式。
本系统评价确定了特定社会认知能力损伤的进展，这是开发靶向干预措施的必要前提。我们发现，在不同人群（例如，中年、SCD 和 MCI 亚型）和领域（SDM、VPT）的社会认知衰退方面，研究不足。
