Guenifi W, Gasmi A, Lacheheb A
Faculté de Médecine, Universite Ferhat Abbas Setif 1 et Service des Maladies Infectieuses, CHU de Sétif;, Sétif, Algérie.
Faculté de Médecine, Universite Ferhat Abbas Setif 1 et Service des Maladies Infectieuses, CHU de Sétif;, Sétif, Algérie.
Rev Med Interne. 2022 Oct;43(10):603-607. doi: 10.1016/j.revmed.2022.07.007. Epub 2022 Jul 26.
Viral hepatitis A is characterized by a wide range of clinical pictures ranging from a completely unapparent infection to a fulminant, potentially fatal hepatitis or the classical icteric form. Hepatitis A can develop in an unusual way and extrahepatic manifestations (neurological, renal, haematological, cholecystitis, acute pancreatitis, vasculitis, etc.) can occasionally complicate the course of the disease. Although hepatitis A infection was identified in the early 1970s, there are few or no studies assessing the actual frequency of these complications. They have been studied mainly through clinical case reports. Currently, since the disease has become more common in adults, these complications are being increasingly observed. We present an update on extrahepatic complications during hepatitis A, which should be known by both specialist doctors (infectiologists internists, hepatologists and others) and general practitioners.
甲型病毒性肝炎的临床症状表现多样，从完全隐匿性感染到暴发性、可能致命的肝炎，或典型的黄疸型肝炎。甲型肝炎可能以不寻常的方式发病，肝外表现（神经、肾脏、血液、胆囊炎、急性胰腺炎、血管炎等）偶尔会使病程复杂化。尽管在20世纪70年代初就已发现甲型肝炎感染，但评估这些并发症实际发生率的研究很少或几乎没有。它们主要是通过临床病例报告进行研究的。目前，由于该疾病在成年人中变得更为常见，这些并发症越来越多地被观察到。我们提供了一份甲型肝炎期间肝外并发症的最新情况，专科医生（感染病学家、内科医生、肝病学家等）和全科医生都应该了解这些情况。
