Department of Neurology, Huashan Hospital, Fudan University, Shanghai, China.
Shanghai Medical College, Fudan University, Shanghai, China.
BMC Neurol. 2022 Jul 29;22(1):283. doi: 10.1186/s12883-022-02794-z.
Lymphoplasmacyte-rich meningioma (LPRM) is a rare form of meningioma characterized by prominent lymphoplasmacytic infiltrates into the tumor. Report of flat growth of LPRM mimicking pachymeningitis is rare in the literature.
A 55-year-old female who suffered from episodes of headache and seizures has been diagnosed with pachymeningitis for 4 years because post contrast brain MRI demonstrated enhanced carpet-like dura lesion in the left frontal lobe. The lesion kept unchanged on yearly follow-ups until a recent brain MRI found the lesion grew significantly into a mass. The lesion was resected and pathology suggested LPRM.
LPRM may present as carpet-like growth pattern on MRI. Long-term follow-up in patients with pachymeningitis is necessary.
淋巴浆细胞丰富型脑膜瘤（LPRM）是一种罕见的脑膜瘤，其特征是肿瘤内有明显的淋巴浆细胞浸润。文献中很少有报道 LPRM 呈扁平生长，类似于肥厚性脑膜炎。
一名 55 岁女性，反复发作头痛和癫痫，4 年来被诊断为肥厚性脑膜炎，因为增强脑 MRI 显示左额叶有增强的地毯样硬脑膜病变。该病变在每年的随访中保持不变，直到最近的脑 MRI 发现病变明显生长成一个肿块。该病变被切除，病理提示淋巴浆细胞丰富型脑膜瘤。
LPRM 在 MRI 上可能表现为地毯样生长模式。肥厚性脑膜炎患者需要长期随访。
