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N7-甲基鸟嘌呤(mG)在癌症中的作用。

Role of N7-methylguanosine (mG) in cancer.

机构信息

Guangzhou Institute of Pediatrics, Guangdong Provincial Key Laboratory of Research in Structural Birth Defect Disease, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, Guangdong, China.

Faculty of Medicine, Macau University of Science and Technology, Macau 999078, China.

出版信息

Trends Cell Biol. 2022 Oct;32(10):819-824. doi: 10.1016/j.tcb.2022.07.001. Epub 2022 Jul 27.

Abstract

N7-methylguanosine (mG) is a significant RNA modification occurring during epigenetic regulation. An increasing number of investigations have proved that the effect of mG in suppressing cancer deserves more attention. Herein, we explore potential valuable targets based on present studies of mG-related cancer to improve disease therapy and prognoses.

摘要

N7-甲基鸟苷(mG)是一种在表观遗传调控过程中发生的重要 RNA 修饰。越来越多的研究证明,mG 在抑制癌症方面的作用值得更多关注。在此,我们基于目前关于 mG 相关癌症的研究,探索潜在的有价值的靶点,以改善疾病的治疗和预后。

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