Department of Medical Records Room, Hebei General Hospital, Shijiazhuang, 050051, Hebei, China.
Department of Neurology, Hebei General Hospital, Shijiazhuang, 050051, Hebei, China.
Acta Neurol Belg. 2023 Jun;123(3):873-883. doi: 10.1007/s13760-022-01976-3. Epub 2022 Jul 30.
The purposes were to establish standardized values for the Auditory Verbal Learning Test (AVLT) in the communities of Shijiazhuang city (China), with particular focus on the influences of age, education and sex, and to detect the discriminant validity data of the AVLT in patients with acute ischemic stroke (AIS).
406 Chinese-speaking subjects (age: 50-84 years old) from Shijiazhuang city, were brought into this study. Using linear regression analyses, standardized values were developed for three variables of interest, including scores on short-term memory (sum of AVLT trials 1-3), delayed recall (AVLT trial 4), and an index representing recognition memory corrected for false-positive identifications (AVLT trial 5). 177 patients with AIS were included to probe the discriminant validity of the AVLT.
The linear regression analysis showed statistically significant effect of age and sex on all trials of the AVLT. Years of education contributed significantly to trial 1-3 and trial 4 but not trial 5. Based on the results obtained, trail 1-3 and trail 4 of AVLT norms were stratified by age (3 strata), education (2 strata), and sex (2 strata). Trail 5 norms were stratified by age (3 strata) and sex (2 strata). Moreover, AIS groups performed significantly worse on most AVLT trials than matched cognitively healthy controls.
Normative data stratified by age, education and sex for the Chinese-speaking community-residents in Shijiazhuang was presented for use in research and clinical settings. The AVLT measures adequately differentiated between the cognitive performance (especially memory decline) of healthy adults and patients with AIS.
建立石家庄市社区人群听觉词语学习测验(AVLT)的标准化值,特别关注年龄、教育和性别对其的影响,并检测 AVLT 在急性缺血性脑卒中(AIS)患者中的鉴别效度数据。
本研究纳入了石家庄市的 406 名汉族受试者(年龄 50-84 岁)。采用线性回归分析,为三个感兴趣的变量(AVLT 测验 1-3 的短期记忆得分、延迟回忆得分和校正错误识别的再认记忆指数)制定了标准化值。纳入 177 例 AIS 患者以探讨 AVLT 的鉴别效度。
线性回归分析显示,年龄和性别对 AVLT 的所有测验均有统计学显著影响。受教育年限对测验 1-3 和测验 4 有显著影响,但对测验 5 无显著影响。基于这些结果,AVLT 测验 1-3 和测验 4 的标准值按年龄(3 个层次)、教育(2 个层次)和性别(2 个层次)进行分层。测验 5 的标准值按年龄(3 个层次)和性别(2 个层次)进行分层。此外,AIS 组在大多数 AVLT 测验上的表现明显差于匹配的认知健康对照组。
为石家庄市汉族社区居民提供了按年龄、教育和性别分层的中文 AVLT 常模,可用于研究和临床环境。AVLT 能够充分区分健康成年人和 AIS 患者的认知表现(尤其是记忆下降)。