Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, United States.
Department of Surgery Mayo Clinic, Rochester, MN, United States.
Front Endocrinol (Lausanne). 2022 Jul 14;13:946870. doi: 10.3389/fendo.2022.946870. eCollection 2022.
Metabolic and bariatric surgery is the most effective therapy for weight loss and improving obesity-related comorbidities, comprising the Roux-en-Y gastric bypass (RYGB), gastric banding, sleeve gastrectomy (SG), and biliopancreatic diversion with duodenal switch. While the effectiveness of weight loss surgery is well-rooted in existing literature, weight recurrence (WR) following bariatric surgery is a concern. Endoscopic bariatric therapy presents an anatomy-preserving and minimally invasive option for managing WR in select cases. In this review article, we will highlight the endoscopic management techniques for WR for the most commonly performed bariatric surgeries in the United States -RYGB and SG. For each endoscopic technique, we will review weight loss outcomes in the short and mid-terms and discuss safety and known adverse events. While there are multiple endoscopic options to help address anatomical issues, patients should be managed in a multidisciplinary approach to address anatomical, nutritional, psychological, and social factors contributing to WR.
代谢和减重手术是减肥和改善肥胖相关合并症的最有效疗法,包括 Roux-en-Y 胃旁路术(RYGB)、胃带术、袖状胃切除术(SG)和胆胰分流十二指肠转位术。虽然减重手术的减肥效果在现有文献中已经得到充分证实,但减重手术后的体重复发(WR)仍然令人担忧。内镜减重治疗为某些特定情况下的 WR 提供了一种保留解剖结构和微创的选择。在这篇综述文章中,我们将重点介绍美国最常进行的两种减重手术——RYGB 和 SG 的 WR 的内镜治疗技术。对于每种内镜技术,我们将回顾短期和中期的减肥效果,并讨论安全性和已知的不良事件。虽然有多种内镜选择可以帮助解决解剖问题,但患者应采用多学科方法进行管理,以解决导致 WR 的解剖、营养、心理和社会因素。