Suppr超能文献

与青少年早期饮酒有关的健康和家庭环境因素:一项基于记录链接、数据驱动、纵向队列研究。

Health and household environment factors linked with early alcohol use in adolescence: a record-linked, data-driven, longitudinal cohort study.

机构信息

Administrative Data Research Wales, Swansea University Medical School, Wales SA2 8PP, UK.

National Centre for Population Health and Wellbeing Research, Swansea University Medical School, Wales, SA2 8PP, UK.

出版信息

Int J Popul Data Sci. 2022 Jul 7;7(1):1717. doi: 10.23889/ijpds.v7i1.1717. eCollection 2022.

Abstract

INTRODUCTION

Early alcohol use has significant association with poor health outcomes. Individual risk factors around early alcohol use have been identified, but a holistic, data-driven investigation into health and household environmental factors on early alcohol use is yet to be undertaken.

OBJECTIVES

This study aims to investigate the relationship between preceding health events, household exposures and early alcohol use during adolescence using a two-stage data-driven approach.

METHODS

In stage one, a study population (N = 1,072) were derived from the Millennium Cohort Study (MCS) Wales (born between 2000-2002). MCS data were first linked with electronic-health records. Factors associated with early (<=eleven years old) alcohol use were identified using feature selection and stepwise logistic regression. In stage two, analogous risk factors from MCS were recreated for whole population (N = 59,231) of children (born between 1998-2002 in the Welsh Demographic Service Dataset) using routine data to predict the alcohol-related health events in hospital or GP records.

RESULTS

Significant risk factors from stage two included poor maternal mental (adjusted odds ratio [aOR] = 1.31) and physical health (aOR = 1.25), living with someone with alcohol-related problem (aOR = 2.16), single-adult household (aOR = 1.45), ever in deprivation (aOR = 1.66), child's high hyperactivity (aOR = 3.57), and conduct disorder (aOR = 3.26). Children with health events, whose health needs are supported (e.g., are taken to the doctor), are at lower risk of early alcohol use.

CONCLUSION

Health events of the family members and the child can act as modifiable exposures and may therefore inform the development of prevention initiatives. Families with known alcohol problems, living in deprivation, experiencing child behavioural problems and those who are not taken to the doctor are at higher risk of early drinking behaviour and should be prioritised for early years support and interventions to target problem drinking in young people.

摘要

引言

早期饮酒与健康不良结局密切相关。已经确定了与早期饮酒有关的个体风险因素,但尚未进行全面的数据驱动研究,以调查健康和家庭环境因素对早期饮酒的影响。

目的

本研究旨在使用两阶段数据驱动方法调查青少年时期之前的健康事件、家庭暴露与早期饮酒之间的关系。

方法

在第一阶段,从千禧年队列研究(MCS)威尔士(2000-2002 年出生)中获得研究人群(N=1072)。首先将 MCS 数据与电子健康记录链接。使用特征选择和逐步逻辑回归确定与早期(<=11 岁)饮酒相关的因素。在第二阶段,使用常规数据为 MCS 中的类似风险因素创建整个人群(1998-2002 年出生于威尔士人口服务数据集的 59231 名儿童),以预测医院或全科医生记录中的与酒精相关的健康事件。

结果

第二阶段的显著风险因素包括母亲心理健康不佳(调整后的优势比[aOR]=1.31)和身体健康不佳(aOR=1.25)、与有酒精相关问题的人同住(aOR=2.16)、单亲家庭(aOR=1.45)、曾经贫困(aOR=1.66)、儿童高度多动(aOR=3.57)和品行障碍(aOR=3.26)。有健康事件的儿童,如果其健康需求得到支持(例如,去看医生),则不太可能早期饮酒。

结论

家庭成员和儿童的健康事件可以作为可改变的暴露因素,因此可以为预防措施的制定提供信息。已知有酗酒问题、生活贫困、有儿童行为问题且未就医的家庭,以及那些未就医的家庭,更有可能出现早期饮酒行为,应优先为其提供早期支持和干预措施,以针对年轻人的问题饮酒行为进行干预。

相似文献

本文引用的文献

5
Epidemiology in wonderland: Big Data and precision medicine.仙境中的流行病学:大数据与精准医学。
Eur J Epidemiol. 2018 Mar;33(3):245-257. doi: 10.1007/s10654-018-0385-9. Epub 2018 Apr 5.
9
Cohort profile: UK Millennium Cohort Study (MCS).队列资料简介:英国千禧年队列研究(MCS)。
Int J Epidemiol. 2014 Dec;43(6):1719-25. doi: 10.1093/ije/dyu001. Epub 2014 Feb 17.
10
Adolescent alcohol use: risks and consequences.青少年饮酒:风险与后果。
Alcohol Alcohol. 2014 Mar-Apr;49(2):160-4. doi: 10.1093/alcalc/agt180. Epub 2014 Jan 8.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验