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医学生对通过基因疗法提高患有遗传疾病儿童福祉的接受度:一项在印度尼西亚开展的研究。

Medical student acceptance on gene therapy to increase children's well-being with genetic diseases: a study in Indonesia.

作者信息

Setyanto Dimas, d'Arqom Annette, Indiastuti Danti Nur, Qurnianingsih Ema, Hasanatuludhhiyah Nurina, Izzah Safira Nur, Nasution Mhd Zamal, Yusof Junaidah

机构信息

Medical Program, Faculty of Medicine, Universitas Airlangga, Surabaya, 60131, Indonesia.

Department of Anatomy, Histology, & Pharmacology, Faculty of Medicine, Universitas Airlangga, Surabaya, 60131, Indonesia.

出版信息

Future Sci OA. 2022 May 30;8(6):FSO800. doi: 10.2144/fsoa-2021-0130. eCollection 2022 Jul.

DOI:10.2144/fsoa-2021-0130
PMID:35909997
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9327639/
Abstract

AIM

Gene therapy is expected to improve patients' quality of life. Medical students need to be aware about this technology as its application is becoming wider.

MATERIALS & METHODS: A web-based survey was conducted to measure the acceptance of Indonesian medical students regarding gene therapy.

RESULTS

Data from 621 valid responses showed that Indonesian medical students have little knowledge of this technology, with 34.4% of them ever heard of gene therapy. However, most of them support the approved gene therapy for health-related matters, but not on the non-health related matters. Their acceptance was determined by the sex, domicile and studentship status.

CONCLUSION

Increasing medical students' knowledge of gene therapy is important to minimize the future conflict of gene therapy application.

摘要

目的

基因治疗有望改善患者的生活质量。随着基因治疗应用范围日益广泛,医学生需要了解这项技术。

材料与方法

开展了一项基于网络的调查,以衡量印度尼西亚医学生对基因治疗的接受程度。

结果

621份有效回复的数据显示,印度尼西亚医学生对这项技术了解甚少,其中34.4%的人听说过基因治疗。然而,他们中的大多数人支持已获批的与健康相关事务的基因治疗,但不支持与非健康相关事务的基因治疗。他们的接受程度取决于性别、居住地址和学生身份。

结论

增加医学生对基因治疗的了解对于尽量减少未来基因治疗应用中的冲突至关重要。

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Gene therapy for cystic fibrosis: new tools for precision medicine.囊性纤维化的基因治疗:精准医学的新工具。
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Characterization of integration frequency and insertion sites of adenovirus DNA into mouse liver genomic DNA following intravenous injection.
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