Pfordt J, Magerl H, Vock R
Z Rechtsmed. 1987;98(1):43-8. doi: 10.1007/BF00200385.
The insecticide propoxur (2-isopropoxyphenyl-N-methylcarbamate) acts by blocking cholinesterase. This inhibition is fast and, unlike that brought about by organophosphorus compounds, reversible. The toxicity of propoxur to man is stated to be low compared with that of parathion. Only a small number of fatal intoxications have been published; at the Würzburg University Institute of Legal Medicine eight cases have been observed since 1978. In seven cases death occurred after deliberate oral ingestion of solutions of propoxur with suicidal intent, while in the other, intoxication was accidental, following inhalation of an aerosol containing propoxur. Organs and body fluids were investigated toxicologically and histologically. The results are presented and discussed. Special attention is paid to the combination of propoxur and alcohol.
杀虫剂残杀威（2-异丙氧基苯基-N-甲基氨基甲酸酯）通过抑制胆碱酯酶起作用。这种抑制作用迅速，而且与有机磷化合物引起的抑制不同，它是可逆的。据说，与对硫磷相比，残杀威对人类的毒性较低。仅有少量关于致命中毒的报道发表；自1978年以来，维尔茨堡大学法医学研究所已观察到8例。其中7例是故意口服含残杀威溶液企图自杀导致死亡，另一例是意外中毒，因吸入了含有残杀威的气雾剂。对器官和体液进行了毒理学和组织学研究。现将结果予以呈现并讨论。特别关注了残杀威与酒精的联合作用。
