Wutzler P, Mücke H, Battke H, Goebel P, Schreiber D
Z Urol Nephrol. 1987 Feb;80(2):105-10.
Animal experimenters investigations on the influence of various solutions of peracetic acid on the epithelium of the urinary bladder were carried out on rabbits. The results of the experiments showed that solutions of peracetic acid up to 0.01% are tolerated nearly without any reaction also under extreme experimental conditions. Higher concentrations of active substances lead to considerable changes of the epithelium of the urinary bladder in form of partly focal, partly diffuse haemorrhagic necrotizing urocystitides. No differences were the result when the commercial 40 percent peracetic acid Wofasteril and a 20 percent peracetic acid without admixture of a stabilizer as primary solution were used. The possible application of peracetic acid as antiseptic for the mucous membrane is discussed.
在兔子身上进行了动物实验，以研究不同浓度过氧乙酸溶液对膀胱上皮的影响。实验结果表明，在极端实验条件下，浓度高达0.01%的过氧乙酸溶液几乎不会引起任何反应。活性物质浓度较高时，会导致膀胱上皮发生相当大的变化，表现为部分局灶性、部分弥漫性出血性坏死性膀胱炎。使用市售40%过氧乙酸Wofasteril和未添加稳定剂的20%过氧乙酸原液作为初始溶液时，结果并无差异。文中还讨论了过氧乙酸作为黏膜防腐剂的可能应用。
