Aldakhil Salman, Mathieu David
Surgery/Neurosurgery, Université de Sherbrooke, Sherbrooke, QC, Canada.
Front Surg. 2022 Jul 14;9:908645. doi: 10.3389/fsurg.2022.908645. eCollection 2022.
The abscopal effect is partial or complete tumor response in a separate site that was not the target of prior local treatment. There have been only 50 well-documented cases from 1960 to 2014. Our case is the first one of presumed low-grade meningioma demonstrating a possible response the abscopal effect after single-fraction stereotactic radiosurgery.
A case of a 70-years-old female with extensive intracranial meningiomatosis who had complete disappearance of all tumors after gamma knife radiosurgery targeting the right petroclival part of the tumor. She had complete resolution of her symptoms, which included hearing loss, headache, ataxia and dysphagia.
The abscopal effect is an extremely rare phenomenon after local radiation therapy of a remote tumor. Our case demonstrates that this can occur in remote meningiomas after single fraction GKRS of a different tumor.
远隔效应是指在先前局部治疗未针对的另一个部位出现部分或完全的肿瘤反应。从1960年至2014年仅有50例记录完备的病例。我们的病例是首例推测为低级别脑膜瘤，在单次立体定向放射外科治疗后显示出可能的远隔效应反应。
一名70岁女性患有广泛颅内脑膜瘤病，在对肿瘤右侧岩斜部进行伽玛刀放射外科治疗后，所有肿瘤完全消失。她的症状完全缓解，这些症状包括听力丧失、头痛、共济失调和吞咽困难。
远隔效应是局部放疗远处肿瘤后极其罕见的现象。我们的病例表明，在不同肿瘤单次伽玛刀放射外科治疗后，这种情况可发生于远处脑膜瘤。
