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噬菌体-宿主相互作用每日报告

Daily Reports on Phage-Host Interactions.

作者信息

Albrycht Kamil, Rynkiewicz Adam A, Harasymczuk Michal, Barylski Jakub, Zielezinski Andrzej

机构信息

Department of Computational Biology, Faculty of Biology, Adam Mickiewicz University, Poznań, Poland.

Department of Traumatology, Orthopaedics and Hand Surgery, University of Medical Sciences, Poznan, Poland.

出版信息

Front Microbiol. 2022 Jul 14;13:946070. doi: 10.3389/fmicb.2022.946070. eCollection 2022.

Abstract

Understanding phage-host relationships is crucial for the study of virus biology and the application of phages in biotechnology and medicine. However, information concerning the range of hosts for bacterial and archaeal viruses is scattered across numerous databases and is difficult to obtain. Therefore, here we present PHD (Phage & Host Daily), a web application that offers a comprehensive, up-to-date catalog of known phage-host associations that allows users to select viruses targeting specific bacterial and archaeal taxa of interest. Our service combines the latest information on virus-host interactions from seven source databases with current taxonomic classification retrieved directly from the groups and institutions responsible for its maintenance. The web application also provides summary statistics on host and virus diversity, their pairwise interactions, and the host range of deposited phages. PHD is updated daily and available at http://phdaily.info or http://combio.pl/phdaily.

摘要

了解噬菌体与宿主的关系对于病毒生物学研究以及噬菌体在生物技术和医学中的应用至关重要。然而,有关细菌和古菌病毒宿主范围的信息分散在众多数据库中,难以获取。因此,我们在此介绍PHD(噬菌体与宿主日报),这是一个网络应用程序,它提供了一个全面、最新的已知噬菌体 - 宿主关联目录,允许用户选择针对特定感兴趣的细菌和古菌分类群的病毒。我们的服务将来自七个源数据库的病毒 - 宿主相互作用的最新信息与直接从负责维护的团体和机构检索到的当前分类学分类相结合。该网络应用程序还提供有关宿主和病毒多样性、它们的成对相互作用以及所存噬菌体宿主范围的汇总统计信息。PHD每日更新,可在http://phdaily.info或http://combio.pl/phdaily上获取。

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