Christen H J, Hanefeld F
Zentralbl Bakteriol Mikrobiol Hyg A. 1987 Feb;263(3):337-42. doi: 10.1016/s0176-6724(87)80088-3.
Erythema-migrans-disease represents a tick-borne borreliosis with a high and widespread incidence according to first epidemiological surveys. The early symptom is a distinctive erythema migrans eventually followed by arthritis and cardiac involvement as well as neurologic complications in the form of lymphocytic meningoradiculitis Garin-Bujadoux-Bannwarth. In a one-year-period we observed 9 children who developed neurologic complications as the predominant feature of erythema-migrans-disease. Eight children suffered from a lymphocytic meningitis and/or a peripheral facial palsy and one child presented with a severe polyradiculoneuritis with complete transverse myelitis. In contrast to adults the clinical course of neurologic manifestations in children seems to be milder and shorter and not associated with the typical painful radiculitis. Acute Bell's palsy seems to be a rather common symptom, whereas other peripheral pareses of the mononeuritis multiplex type were not observed. With respect to the assumed frequency and because of the possibility of antibiotic therapy, erythema-migrans-disease should be ruled out in any case of so-called idiopathic facial palsy or aseptic meningitis, which are frequently encountered in children.
根据首次流行病学调查，游走性红斑病是一种由蜱传播的莱姆病，发病率高且广泛。早期症状是一种独特的游走性红斑，最终可发展为关节炎、心脏受累以及以淋巴细胞性脑膜炎神经根炎（加林-布雅杜-班沃思综合征）形式出现的神经系统并发症。在一年时间里，我们观察到9名儿童以游走性红斑病的神经系统并发症为主要特征。8名儿童患有淋巴细胞性脑膜炎和/或周围性面瘫，1名儿童表现为严重的多神经根神经炎并伴有完全性横贯性脊髓炎。与成人不同，儿童神经系统表现的临床病程似乎更轻、更短，且与典型的疼痛性神经根炎无关。急性贝尔面瘫似乎是一种相当常见的症状，而未观察到其他多发性单神经炎类型的周围性麻痹。鉴于其假定的发病率以及抗生素治疗的可能性，在儿童中经常遇到的任何所谓特发性面瘫或无菌性脑膜炎病例中，都应排除游走性红斑病。
