Doby J M, Anderson J F, Couatarmanac'h A, Magnarelli L A, Martin A
Zentralbl Bakteriol Mikrobiol Hyg A. 1987 Feb;263(3):488-90. doi: 10.1016/s0176-6724(87)80116-5.
The first documented case of Lyme disease to have originated in Canada is presented. A 51-year old French female nurse visited Quebec, Canada from 20 July to 5 August, 1984 and contracted Lyme disease. She reported an insect bite on 3 August 1984 on the back of her knee with erythema chronicum migrans appearing at the site of the bite on 5 August 1984. The patient presented with meningeal lymphocytic reaction near the end of September, 1984. Total Ig serum titers in indirect immunofluorescence tests on 1 October 1984, 10 October 1984, and 10 January 1985 were 1/512, 1/2048 and 1/16,384, respectively.
本文介绍了首例有记录的起源于加拿大的莱姆病病例。一名51岁的法国女护士于1984年7月20日至8月5日访问了加拿大魁北克省，并感染了莱姆病。她报告称1984年8月3日膝盖后部被昆虫叮咬，8月5日在叮咬部位出现慢性游走性红斑。该患者于1984年9月底出现脑膜淋巴细胞反应。1984年10月1日、1984年10月10日和1985年1月10日的间接免疫荧光试验中，血清总Ig滴度分别为1/512、1/2048和1/16384。
