Magnarelli L A, Anderson J F, Chappell W A
Yale J Biol Med. 1984 Jul-Aug;57(4):619-26.
An indirect immunofluorescence test was used during 1982-1983 to identify antibodies to Lyme disease spirochetes in humans, white-footed mice, and raccoons. Serologic tests detected IgM or total Ig antibodies in serum samples from 67 persons. Onset of illness, as marked by erythema chronicum migrans (ECM), occurred mainly during July and August. The majority of the persons with Lyme disease lived in south central and southeastern Connecticut. Analyses also verified prior spirochetal infections in 29 of 323 (9 percent) white-footed mice and in three of 34 (9 percent) raccoons captured at sites with or without evidence of human infections. Results indicate potential for Lyme disease at numerous localities in Connecticut.
1982年至1983年期间,采用间接免疫荧光试验来鉴定人类、白足鼠和浣熊体内抗莱姆病螺旋体的抗体。血清学检测在67人的血清样本中检测到IgM或总Ig抗体。以慢性游走性红斑(ECM)为标志的疾病发作主要发生在7月和8月。大多数莱姆病患者居住在康涅狄格州中南部和东南部。分析还证实,在有或无人类感染证据的地点捕获的323只白足鼠中有29只(9%)以及34只浣熊中有3只(9%)曾感染过螺旋体。结果表明康涅狄格州许多地方都有莱姆病的发病风险。