Dang Xiaozhi, Zhang Xin, Gao Yi, Song Hongping
Department of Ultrasound, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, China.
J Breast Cancer. 2022 Aug;25(4):344-348. doi: 10.4048/jbc.2022.25.e32. Epub 2022 Jul 8.
Breast imaging techniques are used to assess the tumor response to neoadjuvant treatment (NAT), which is increasingly one of the preferred therapeutic options and increases the rate of breast conservation for breast cancer. Herein, we report a case in which a woman was diagnosed with invasive ductal carcinoma in the left breast and received NAT before surgery. Automated breast ultrasound (AB US) was regularly performed before and during the NAT to evaluate the tumor response to NAT by measuring diameter changes and volume reductions of the tumor. Images showed that the tumor size was significantly reduced and disappeared after 7 cycles of NAT, except for macrocalcification. Postoperative histopathological examination confirmed that there were no residual tumor cells. We found that AB US overcame the limitations of handheld US, such as operator dependence, poor reproducibility and limited field of view, and can be an alternative modality to assess the tumor response of NAT in the absence of magnetic resonance imaging (MRI) instruments.
乳腺成像技术用于评估肿瘤对新辅助治疗（NAT）的反应，新辅助治疗日益成为首选的治疗选择之一，并且提高了乳腺癌保乳率。在此，我们报告一例病例，一名女性被诊断为左乳浸润性导管癌，术前接受了新辅助治疗。在新辅助治疗前和治疗期间定期进行自动乳腺超声（AB US）检查，通过测量肿瘤直径变化和体积缩小来评估肿瘤对新辅助治疗的反应。图像显示，经过7个周期的新辅助治疗后，除大钙化外，肿瘤大小显著缩小并消失。术后组织病理学检查证实无残留肿瘤细胞。我们发现，自动乳腺超声克服了手持超声的局限性，如操作者依赖性、重复性差和视野有限等，在没有磁共振成像（MRI）设备的情况下，它可以作为评估新辅助治疗肿瘤反应的替代方法。
