• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

脊柱快速进展性骨关节炎:首例报告病例的经验教训。

Rapidly destructive osteoarthritis of the spine: lessons learned from the first reported case.

机构信息

IRCCS Istituto Ortopedico Galeazzi, Milano, Italy.

Department of Orthopaedics and Trauma Surgery, RWTH Aachen University Clinic, Aachen, Germany.

出版信息

BMC Musculoskelet Disord. 2022 Aug 1;23(1):735. doi: 10.1186/s12891-022-05686-y.

DOI:10.1186/s12891-022-05686-y
PMID:35915481
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9340694/
Abstract

BACKGROUND

Rapidly Destructive Osteoarthritis (RDOA) has been described for the hip and shoulder joints and is characterized by a quickly developing bone edema followed by extensive remodeling and joint destruction. Confronted with a similarly evolving case of endplate edema and destruction of the disk space, we offer the first described case of spinal RDOA and illustrate the challenges it presented, along with the strategies we put in place to overcome them.

CASE PRESENTATION

We present a case of spinal RDOA that, also due to the delay in the diagnoses, underwent multiple revisions for implant failure with consequent coronal and sagittal imbalance. A 37-years-old, otherwise healthy female presented with atraumatic low back pain: after initial conservative treatment, subsequent imaging showed rapidly progressive endplate erosion and a scoliotic deformity. After surgical treatment, the patient underwent numerous revisions for pseudoarthrosis, coronal and sagittal imbalance and junctional failure despite initially showing a correct alignement after each surgery. As a mechanic overload from insufficient correction of the alignement of the spine was ruled out, we believe that the multiple complications were caused by an impairment in the bone structure and thus, reviewing old imaging, diagnosed the patient with spinal RDOA. In case of spinal RDOA, particular care should be placed in the choice of extent and type of instrumentation in order to prevent re-intervention.

CONCLUSION

Spinal RDOA is characterized by a quickly developing edema of the vertebral endplates followed by a destruction of the disk space within months from the first diagnosis. The disease progresses in the involved segment and to the adjacent disks despite surgical therapy. The surgical planning should take the impaired bone structure account and the use of large interbody cages or 4-rod constructs should be considered to obtain a stable construct.

摘要

背景

快速破坏性骨关节炎(RDOA)已在髋关节和肩关节中被描述,其特征是迅速发展的骨水肿,随后是广泛的重塑和关节破坏。在面对一个类似的进展性终板水肿和椎间盘空间破坏的病例时,我们提供了首例脊柱 RDOA 的描述性病例,并说明了它所带来的挑战,以及我们为克服这些挑战而采取的策略。

病例介绍

我们介绍了一例脊柱 RDOA 病例,由于诊断延误,该病例经历了多次植入物失败的翻修,导致冠状和矢状面失衡。一名 37 岁、健康状况良好的女性出现无创伤性腰痛:初始保守治疗后,后续影像学显示终板迅速进行性侵蚀和脊柱侧凸畸形。手术治疗后,尽管每次手术后患者的排列都得到了正确的矫正,但仍因假关节、冠状和矢状面失衡以及交界处失败而经历了多次翻修。由于机械性过载是由脊柱排列矫正不足引起的可能性被排除,我们认为,这些多次并发症是由骨结构受损引起的,因此,回顾旧的影像学,诊断该患者患有脊柱 RDOA。在脊柱 RDOA 的情况下,应特别注意选择器械的范围和类型,以防止再次干预。

结论

脊柱 RDOA 的特征是在最初诊断后的数月内,椎体终板迅速发展的水肿,随后是椎间盘空间的破坏。尽管进行了手术治疗,疾病仍在受累节段和相邻椎间盘进展。手术规划应考虑到受损的骨结构,并应考虑使用大的椎间笼或 4 棒结构来获得稳定的结构。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a3e/9341148/05a4c0346368/12891_2022_5686_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a3e/9341148/73807c02b17a/12891_2022_5686_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a3e/9341148/d02295fe6600/12891_2022_5686_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a3e/9341148/f472cbda4db9/12891_2022_5686_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a3e/9341148/2e0a836718a9/12891_2022_5686_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a3e/9341148/047ad6de91cf/12891_2022_5686_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a3e/9341148/b5a718e1b03b/12891_2022_5686_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a3e/9341148/7831dda16da9/12891_2022_5686_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a3e/9341148/d17bddeab882/12891_2022_5686_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a3e/9341148/05a4c0346368/12891_2022_5686_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a3e/9341148/73807c02b17a/12891_2022_5686_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a3e/9341148/d02295fe6600/12891_2022_5686_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a3e/9341148/f472cbda4db9/12891_2022_5686_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a3e/9341148/2e0a836718a9/12891_2022_5686_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a3e/9341148/047ad6de91cf/12891_2022_5686_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a3e/9341148/b5a718e1b03b/12891_2022_5686_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a3e/9341148/7831dda16da9/12891_2022_5686_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a3e/9341148/d17bddeab882/12891_2022_5686_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a3e/9341148/05a4c0346368/12891_2022_5686_Fig9_HTML.jpg

相似文献

1
Rapidly destructive osteoarthritis of the spine: lessons learned from the first reported case.脊柱快速进展性骨关节炎:首例报告病例的经验教训。
BMC Musculoskelet Disord. 2022 Aug 1;23(1):735. doi: 10.1186/s12891-022-05686-y.
2
The effectiveness of selective thoracic fusion for treating adolescent idiopathic scoliosis: a systematic review protocol.选择性胸椎融合术治疗青少年特发性脊柱侧凸的有效性:一项系统评价方案
JBI Database System Rev Implement Rep. 2015 Nov;13(11):4-16. doi: 10.11124/jbisrir-2015-2338.
3
Radiological evaluation of anterior lumbar fusion using PEEK cages with adjacent vertebral autograft in spinal deformity long fusion surgeries.在脊柱畸形长节段融合手术中使用聚醚醚酮椎间融合器结合相邻椎体自体骨移植进行腰椎前路融合的影像学评估。
Eur Spine J. 2015 Apr;24(4):791-9. doi: 10.1007/s00586-014-3745-5. Epub 2015 Jan 25.
4
[Mid-term results of 360-degree lumbar spondylodesis with the use of a tantalum implant for disc replacement].使用钽植入物进行椎间盘置换的360度腰椎融合术的中期结果
Acta Chir Orthop Traumatol Cech. 2009 Oct;76(5):388-93.
5
Cotrel-Dubousset instrumentation in neuromuscular scoliosis.Cotrel-Dubousset 器械在神经肌肉型脊柱侧凸中的应用。
Eur Spine J. 2011 May;20 Suppl 1(Suppl 1):S75-84. doi: 10.1007/s00586-011-1758-x. Epub 2011 Mar 15.
6
Overpowering posterior lumbar instrumentation and fusion with hyperlordotic anterior lumbar interbody cages followed by posterior revision: a preliminary feasibility study.使用前凸型腰椎椎间融合器增强后路腰椎内固定和融合,随后进行后路翻修:一项初步可行性研究。
J Neurosurg Spine. 2017 Dec;27(6):650-660. doi: 10.3171/2017.5.SPINE16926. Epub 2017 Sep 29.
7
Decision making in surgical treatment of chronic low back pain: the performance of prognostic tests to select patients for lumbar spinal fusion.慢性下腰痛手术治疗中的决策:用于选择腰椎融合术患者的预后测试的效能
Acta Orthop Suppl. 2013 Feb;84(349):1-35. doi: 10.3109/17453674.2012.753565.
8
Poor Bone Quality, Multilevel Surgery, and Narrow and Tall Cages Are Associated with Intraoperative Endplate Injuries and Late-onset Cage Subsidence in Lateral Lumbar Interbody Fusion: A Systematic Review.骨质量差、多节段手术、以及狭窄且高的 cage 与侧路腰椎间融合术中终板损伤和迟发性 cage 下沉有关:一项系统评价。
Clin Orthop Relat Res. 2022 Jan 1;480(1):163-188. doi: 10.1097/CORR.0000000000001915.
9
Comparative analysis of 3 surgical strategies for adult spinal deformity with mild to moderate sagittal imbalance.成人脊柱畸形伴轻至中度矢状面失衡的三种手术策略的比较分析
J Neurosurg Spine. 2018 Jan;28(1):40-49. doi: 10.3171/2017.5.SPINE161370. Epub 2017 Nov 3.
10
Influence of cage geometry on sagittal alignment in instrumented posterior lumbar interbody fusion.椎间融合器几何形状对后路腰椎椎间融合内固定矢状面排列的影响。
Spine (Phila Pa 1976). 2003 Aug 1;28(15):1693-9. doi: 10.1097/01.BRS.0000083167.78853.D5.

引用本文的文献

1
Radiological Spinopelvic Parameters Can Be Risk Factors for Early Total Hip Replacement After Spine Fusion.放射学脊柱骨盆参数可能是脊柱融合术后早期全髋关节置换的危险因素。
Int J Spine Surg. 2024 Nov 8;18(5):589-594. doi: 10.14444/8681.

本文引用的文献

1
Effects of the Local Bone Renin-Angiotensin System on Titanium-Particle-Induced Periprosthetic Osteolysis.局部骨肾素-血管紧张素系统对钛颗粒诱导的假体周围骨溶解的影响。
Front Pharmacol. 2021 Jun 24;12:684375. doi: 10.3389/fphar.2021.684375. eCollection 2021.
2
Bisphosphonates after denosumab withdrawal reduce the vertebral fractures incidence.地诺单抗停药后使用双膦酸盐可降低椎体骨折发生率。
Eur J Endocrinol. 2021 Aug 4;185(3):387-396. doi: 10.1530/EJE-21-0157.
3
Incidence of adjacent-segment surgery following stand-alone lateral lumbar interbody fusion.
单纯腰椎外侧椎间融合术后相邻节段手术的发生率
J Neurosurg Spine. 2021 Jun 18;35(3):270-274. doi: 10.3171/2020.12.SPINE201218. Print 2021 Sep 1.
4
Anterior Lumbar Interbody Fusion (ALIF) L5-S1 with overpowering of posterior lumbosacral instrumentation and fusion mass: a reliable solution in revision spine surgery.后路腰骶部内固定和融合过度导致前路腰椎体间融合(ALIF)L5-S1:翻修脊柱手术中的可靠解决方案。
Eur Spine J. 2021 Aug;30(8):2323-2332. doi: 10.1007/s00586-021-06888-z. Epub 2021 Jun 3.
5
Comparison of degenerative lumbar scoliosis correction and risk for mechanical failure using posterior 2-rod instrumentation versus 4-rod instrumentation and interbody fusion.后路 2 棒与 4 棒内固定系统及椎间融合治疗退行性腰椎侧凸的疗效比较及器械失败风险分析
Eur Spine J. 2021 Jul;30(7):1965-1977. doi: 10.1007/s00586-021-06870-9. Epub 2021 May 16.
6
Bone turnover markers in the early stage of rapidly progressive osteoarthritis of the hip.髋关节快速进展性骨关节炎早期的骨转换标志物
Eur J Rheumatol. 2021 Apr;8(2):57-61. doi: 10.5152/eurjrheum.2020.20046.
7
Major complications in extreme lateral interbody fusion access: multicentric study by Italian S.O.L.A.S. group.极外侧椎间融合入路的主要并发症:意大利 S.O.L.A.S. 小组的多中心研究。
Eur Spine J. 2021 Jan;30(1):208-216. doi: 10.1007/s00586-020-06542-0. Epub 2020 Aug 3.
8
The mysteries of rapidly destructive arthrosis of the hip joint: a systemic literature review.髋关节快速破坏性关节炎的奥秘:一项系统性文献综述
Ann Palliat Med. 2020 May;9(3):1220-1229. doi: 10.21037/apm.2020.03.17. Epub 2020 Mar 31.
9
Prone single-position extreme lateral interbody fusion (Pro-XLIF): preliminary results.俯卧位单节段极外侧椎间融合术(Pro-XLIF):初步结果。
Eur Spine J. 2020 Feb;29(Suppl 1):6-13. doi: 10.1007/s00586-020-06303-z. Epub 2020 Jan 28.
10
Useful and innovative methods for the treatment of postoperative coronal malalignment in adult scoliosis: the "kickstand rod" and "tie rod" procedures.用于治疗成人脊柱侧弯术后冠状面失衡的有效且创新的方法:“撑脚杆”和“拉杆”手术。
Eur Spine J. 2020 Apr;29(4):849-859. doi: 10.1007/s00586-019-06285-7. Epub 2020 Jan 6.