• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

腹腔镜结直肠癌手术中术中限制性与传统液体管理的术后结局

Post-operative outcomes of intra-operative restrictive and conventional fluid management in laparoscopic colorectal cancer surgery.

作者信息

Erdogan-Ongel Elif, Coskun Nilufer, Meric Ayse Hilal, Goksoy Beslen, Bakan Nurten

机构信息

Department of Anaesthesiology and Reanimation, Sancaktepe Martyr Prof. Dr. Ilhan Varank Education and Research Hospital, Istanbul, Turkey.

Department of General Surgery, Sancaktepe Martyr Prof. Dr. Ilhan Varank Education and Research Hospital, Istanbul, Turkey.

出版信息

J Minim Access Surg. 2023 Apr-Jun;19(2):239-244. doi: 10.4103/jmas.jmas_19_22.

DOI:10.4103/jmas.jmas_19_22
PMID:35915517
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10246644/
Abstract

CONTEXT

Intra-operative fluid management has been shown to significantly alter a patient's clinical condition in peri-operative care. Studies in the literature that investigated the effects of different amounts of intra-operative fluids on outcomes reported conflicting results.

AIMS

To compare the post-operative results of intra-operative restrictive and conventional fluid administrations in laparoscopic colorectal cancer surgery.

SETTINGS AND DESIGN

All patients with ASA I, II and III, and those who had undergone laparoscopic colorectal cancer surgery were included. It was a retrospective, cohort study.

SUBJECTS AND METHODS

A review of laparoscopic colorectal cancer surgeries performed by the same fellow-trained colorectal surgeon with different anaesthesiologists between 1 January, 2018 and 30 November, 2021.

RESULTS

In total 80 patients were analysed; 2 patients were excluded, 28 patients were in restrictive (Group R) and 50 patients were in the conventional (Group C) group. The median age of all patients was 63 years and 74% were male. The median (interquartile ranges 25 to 75) intra-operative fluid administration was significantly different between groups; 3 ml/kg/h in Group R, and 7.2 ml/kg/h in Group C. (P < 0.001) Patients in Group C had significantly high post-operative intensive care unit admission (P < 0.05), and hospital length of stay (P = 0.005) compared to Group R.

CONCLUSIONS

Intra-operative fluid management was significantly associated with post-operative hospital length of stay and intensive care unit admission. Excessive intra-operative fluid management should be avoided in daily practice to improve the outcomes of laparoscopic colorectal cancer surgery.

摘要

背景

术中液体管理已被证明在围手术期护理中会显著改变患者的临床状况。文献中研究不同术中液体量对结局影响的研究报告了相互矛盾的结果。

目的

比较腹腔镜结直肠癌手术中术中限制性液体管理和传统液体管理的术后结果。

设置与设计

纳入所有ASA I、II和III级且接受过腹腔镜结直肠癌手术的患者。这是一项回顾性队列研究。

研究对象与方法

回顾了同一位接受过专科培训的结直肠外科医生在2018年1月1日至2021年11月30日期间与不同麻醉医生进行的腹腔镜结直肠癌手术。

结果

共分析了80例患者;排除2例患者,28例患者为限制性补液组(R组),50例患者为传统补液组(C组)。所有患者的中位年龄为63岁,74%为男性。两组术中液体输注量的中位数(四分位数间距25至75)有显著差异;R组为3 ml/kg/h,C组为7.2 ml/kg/h。(P < 0.001)与R组相比,C组患者术后重症监护病房入住率显著更高(P < 0.05),住院时间也更长(P = 0.005)。

结论

术中液体管理与术后住院时间和重症监护病房入住率显著相关。日常实践中应避免术中过度液体管理,以改善腹腔镜结直肠癌手术的结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d9a/10246644/c0a5851c4bff/JMAS-19-239-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d9a/10246644/c0a5851c4bff/JMAS-19-239-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d9a/10246644/c0a5851c4bff/JMAS-19-239-g001.jpg

相似文献

1
Post-operative outcomes of intra-operative restrictive and conventional fluid management in laparoscopic colorectal cancer surgery.腹腔镜结直肠癌手术中术中限制性与传统液体管理的术后结局
J Minim Access Surg. 2023 Apr-Jun;19(2):239-244. doi: 10.4103/jmas.jmas_19_22.
2
Effect of liberal versus restrictive fluid therapy on intraoperative lactate levels in robot- assisted colorectal surgery.自由液体疗法与限制性液体疗法对机器人辅助结直肠癌手术中术中乳酸水平的影响。
Indian J Anaesth. 2020 Jul;64(7):599-604. doi: 10.4103/ija.IJA_401_20. Epub 2020 Jul 1.
3
Is estimated intra-operative blood loss a reliable predictor of surgical outcomes in laparoscopic colorectal cancer surgery?估计术中失血量是腹腔镜结直肠癌手术手术结果的可靠预测指标吗?
Scott Med J. 2016 Aug;61(3):167-170. doi: 10.1177/0036933015597174. Epub 2015 Jul 24.
4
Goal-directed fluid therapy on laparoscopic colorectal surgery within enhanced recovery after surgery program.手术后加速康复计划下腹腔镜结直肠手术的目标导向液体治疗
Rev Esp Anestesiol Reanim (Engl Ed). 2019 May;66(5):259-266. doi: 10.1016/j.redar.2019.01.007. Epub 2019 Mar 10.
5
Optimal use of antiplatelet agents, especially aspirin, in the perioperative management of colorectal cancer patients undergoing laparoscopic colorectal resection.优化抗血小板药物(尤其是阿司匹林)在接受腹腔镜结直肠切除术的结直肠癌患者围手术期管理中的应用。
World J Surg Oncol. 2019 Jun 1;17(1):92. doi: 10.1186/s12957-019-1634-4.
6
Laparoscopic colorectal surgery: Is it beneficial in the over 80s?腹腔镜结直肠手术:对80岁以上老人有益吗?
Scott Med J. 2016 Aug;61(3):132-135. doi: 10.1177/0036933015597175. Epub 2015 Jul 23.
7
Fast-track laparoscopic surgery: A better option for treating colorectal cancer than conventional laparoscopic surgery.快速康复腹腔镜手术:治疗结直肠癌比传统腹腔镜手术更好的选择。
Oncol Lett. 2015 Jul;10(1):443-448. doi: 10.3892/ol.2015.3166. Epub 2015 Apr 29.
8
An individualised versus a conventional pneumoperitoneum pressure strategy during colorectal laparoscopic surgery: rationale and study protocol for a multicentre randomised clinical study.结直肠腹腔镜手术中个体化与传统气腹压力策略:一项多中心随机临床研究的原理与研究方案
Trials. 2019 Apr 3;20(1):190. doi: 10.1186/s13063-019-3255-1.
9
Laparoscopic versus conventional palliative resection for incurable, symptomatic stage IV colorectal cancer: impact on short-term results.腹腔镜手术与传统姑息性切除术治疗无法治愈的有症状的IV期结直肠癌:对短期结果的影响
Surg Laparosc Endosc Percutan Tech. 2011 Jun;21(3):184-7. doi: 10.1097/SLE.0b013e31821db75e.
10
Utility and short-term outcomes of hand-assisted laparoscopic colorectal surgery: a single-institution experience in 1103 patients.手助腹腔镜结直肠手术的实用性和短期结果:单中心 1103 例经验。
Dis Colon Rectum. 2011 Sep;54(9):1076-81. doi: 10.1007/DCR.0b013e3182155904.

本文引用的文献

1
Effect of fluid strategy on stroke volume, cardiac output, and fluid responsiveness in adult patients undergoing major abdominal surgery: a sub-study of the Restrictive versus Liberal Fluid Therapy in Major Abdominal Surgery (RELIEF) trial.液体管理策略对接受腹部大手术成年患者每搏输出量、心输出量及液体反应性的影响:腹部大手术中限制性与开放性液体治疗(RELIEF)试验的一项子研究
Br J Anaesth. 2021 Apr;126(4):818-825. doi: 10.1016/j.bja.2021.01.011. Epub 2021 Feb 23.
2
Goal-directed fluid therapy on laparoscopic colorectal surgery within enhanced recovery after surgery program.手术后加速康复计划下腹腔镜结直肠手术的目标导向液体治疗
Rev Esp Anestesiol Reanim (Engl Ed). 2019 May;66(5):259-266. doi: 10.1016/j.redar.2019.01.007. Epub 2019 Mar 10.
3
Comparison of conventional fluid management with PVI-based goal-directed fluid management in elective colorectal surgery.择期结直肠手术中传统液体管理与基于脉压变异度的目标导向液体管理的比较。
J Clin Monit Comput. 2019 Apr;33(2):249-257. doi: 10.1007/s10877-018-0163-y. Epub 2018 Jun 14.
4
Restrictive versus Liberal Fluid Therapy for Major Abdominal Surgery.限制与自由液体治疗用于大型腹部手术。
N Engl J Med. 2018 Jun 14;378(24):2263-2274. doi: 10.1056/NEJMoa1801601. Epub 2018 May 9.
5
Effect of isotonic versus hypotonic maintenance fluid therapy on urine output, fluid balance, and electrolyte homeostasis: a crossover study in fasting adult volunteers.等张与低张维持液治疗对尿量、液体平衡和电解质稳态的影响:禁食成年志愿者的交叉研究。
Br J Anaesth. 2017 Jun 1;118(6):892-900. doi: 10.1093/bja/aex118.
6
Goal-directed Fluid Therapy Does Not Reduce Primary Postoperative Ileus after Elective Laparoscopic Colorectal Surgery: A Randomized Controlled Trial.目标导向液体治疗不能降低择期腹腔镜结直肠手术后的原发性术后肠梗阻:一项随机对照试验。
Anesthesiology. 2017 Jul;127(1):36-49. doi: 10.1097/ALN.0000000000001663.
7
Population-based Assessment of Intraoperative Fluid Administration Practices Across Three Surgical Specialties.基于人群的三个外科专业术中液体输注实践评估。
Ann Surg. 2017 May;265(5):930-940. doi: 10.1097/SLA.0000000000001745.
8
Restrictive versus liberal fluid therapy in major abdominal surgery (RELIEF): rationale and design for a multicentre randomised trial.腹部大手术中限制性与开放性液体治疗(RELIEF):一项多中心随机试验的原理与设计
BMJ Open. 2017 Mar 3;7(3):e015358. doi: 10.1136/bmjopen-2016-015358.
9
Perioperative Fluid Utilization Variability and Association With Outcomes: Considerations for Enhanced Recovery Efforts in Sample US Surgical Populations.围手术期液体使用的变异性及其与结局的关联:美国部分外科手术人群强化康复措施的考量
Ann Surg. 2016 Mar;263(3):502-10. doi: 10.1097/SLA.0000000000001402.
10
Estimate of the global volume of surgery in 2012: an assessment supporting improved health outcomes.2012 年全球手术量估计:支持改善健康结果的评估。
Lancet. 2015 Apr 27;385 Suppl 2:S11. doi: 10.1016/S0140-6736(15)60806-6. Epub 2015 Apr 26.