Gastrointestinal Surgery, People's Hospital of Wenjiang District, 611130 Chengdu City, Sichuan Province, China.
Comput Math Methods Med. 2022 Jul 23;2022:8234769. doi: 10.1155/2022/8234769. eCollection 2022.
To explore the application value of the nutrition support team in chemotherapy period of colon cancer based on the internet multidisciplinary treatment mode.
For the method of retrospective study, 90 patients with colon cancer admitted to our hospital from August 2018 to August 2020 were selected as the study subjects. They were equally divided into the experimental group ( = 45) and the control group ( = 45) according to the order of initials and the method of parity group. The control group was given conventional nutrition support, and the experimental group was given the nutrition support under the internet multidisciplinary treatment mode. The serum tumor marker levels (CEA and CA19-9), immune function indexes, nutrition indicators, and the incidence of adverse reactions were compared between the two groups before and after intervention.
The serum tumor marker levels in the experimental group after intervention were significantly lower than those in the control group ( < 0.001). The immune function indexes in the experimental group after intervention were significantly better than those in the control group ( < 0.001). The nutrition indicators in the experimental group after intervention were significantly better than those in the control group ( < 0.001). The incidence of gastrointestinal adverse reactions above grade 2 in the experimental group was significantly lower than that in the control group ( < 0.05). There were 20 patients with myelosuppression, 2 patients with neurotoxicity, and 1 patient with hand and foot syndrome in the experimental group, while 22 patients with myelosuppression, 4 patients with neurotoxicity, and 2 patients with hand and foot syndrome in the control group, with no significant difference in the incidence of adverse reactions between the two groups ( > 0.05).
The nutrition support team under the internet multidisciplinary treatment mode can improve the immune function of chemotherapy patients with colon cancer and enhance their nutritional level, thereby reducing the incidence of adverse reactions and improving the chemotherapy effects.
探讨基于互联网多学科治疗模式的营养支持团队在结肠癌化疗期的应用价值。
采用回顾性研究方法，选取 2018 年 8 月至 2020 年 8 月我院收治的 90 例结肠癌患者为研究对象，按照首字母顺序和配对组方法将其等分为实验组（n = 45）和对照组（n = 45）。对照组给予常规营养支持，实验组给予互联网多学科治疗模式下的营养支持。比较两组患者干预前后的血清肿瘤标志物水平（CEA 和 CA19-9）、免疫功能指标、营养指标和不良反应发生率。
实验组干预后的血清肿瘤标志物水平明显低于对照组（<0.001），实验组干预后的免疫功能指标明显优于对照组（<0.001），实验组干预后的营养指标明显优于对照组（<0.001），实验组 2 级以上胃肠道不良反应发生率明显低于对照组（<0.05）。实验组有 20 例患者出现骨髓抑制，2 例患者出现神经毒性，1 例患者出现手足综合征，对照组有 22 例患者出现骨髓抑制，4 例患者出现神经毒性，2 例患者出现手足综合征，两组不良反应发生率差异无统计学意义（>0.05）。
互联网多学科治疗模式下的营养支持团队可改善结肠癌化疗患者的免疫功能，增强其营养水平，从而降低不良反应发生率，提高化疗效果。
