Department of Chemistry, Birla Institute of Technology, Mesra, Ranchi-835215, Jharkhand, India.
JBRA Assist Reprod. 2023 Mar 30;27(1):92-96. doi: 10.5935/1518-0557.20220019.
COVID-19 has emerged as the biggest pandemic of the world of all times. Its death toll is rising globally. COVID-19 mostly affects the lungs because the virus enters the host cells via the receptor for the ACE2 enzyme, which is also present in other organs of the human body. ACE2 plays the main role in the degradation of Ang II, resulting in the formation of angiotensin 1-7 (Ang 1-7) which maintains the level of Ang II. This communication gives an assessment of reproductive system functioning and its effects by the COVID-19 exposure. It is important to maintain the wellbeing for healthy nourishment of the fetus and safe delivery along with post health issues. ACE2 enzyme metabolism is expressed in the female reproductive system, and it may be potential target of COVID-19 exposure.
新冠疫情已成为全球有史以来最大的一次大流行。其全球死亡人数正在上升。新冠病毒主要影响肺部,因为病毒通过 ACE2 酶的受体进入宿主细胞,而 ACE2 酶的受体也存在于人体的其他器官中。ACE2 在 Ang II 的降解中起主要作用,导致血管紧张素 1-7(Ang 1-7)的形成,从而维持 Ang II 的水平。本通讯评估了 COVID-19 暴露对生殖系统功能及其影响。为了胎儿的健康营养和安全分娩以及产后健康问题,保持健康是很重要的。ACE2 酶代谢在女性生殖系统中表达,它可能是 COVID-19 暴露的潜在靶点。