Suppr超能文献

用于预防冠状病毒表面污染的纳米复合涂层。

Nanocomposite coatings for the prevention of surface contamination by coronavirus.

机构信息

Department of Materials Engineering, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

Ilse Katz Institute for Nanoscale Science & Technology, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

出版信息

PLoS One. 2022 Aug 2;17(8):e0272307. doi: 10.1371/journal.pone.0272307. eCollection 2022.

Abstract

The current Covid-19 pandemic has a profound impact on all aspects of our lives. Aside from contagion by aerosols, the presence of the SARS-CoV-2 is ubiquitous on surfaces that millions of people handle daily. Therefore, controlling this pandemic involves the reduction of potential infections via contaminated surfaces. We developed antiviral surfaces by preparing suspensions of copper and cupric oxide nanoparticles in two different polymer matrices, poly(methyl methacrylate) and polyepoxide. For total copper contents as low as 5%, the composite material showed remarkable antiviral properties against the HCoV-OC43 human coronavirus and against a model lentivirus and proved well-resistant to accelerated aging conditions. Importantly, we showed that the Cu/CuO mixture showed optimal performances. This product can be implemented to produce a simple and inexpensive coating with long-term antiviral properties and will open the way to developing surface coatings against a broad spectrum of pathogens including SARS-CoV-2.

摘要

当前的 COVID-19 大流行对我们生活的方方面面都产生了深远的影响。除了气溶胶传播外,SARS-CoV-2 无处不在,在数百万人每天接触的表面上都存在。因此,控制这种大流行需要通过受污染的表面减少潜在的感染。我们通过在两种不同的聚合物基质(聚甲基丙烯酸甲酯和聚环氧化物)中制备铜和氧化铜纳米粒子的悬浮液来开发抗病毒表面。对于总铜含量低至 5%的复合材料,该复合材料对 HCoV-OC43 人类冠状病毒和一种模型慢病毒表现出显著的抗病毒特性,并且对加速老化条件具有良好的抗性。重要的是,我们表明 Cu/CuO 混合物表现出最佳性能。该产品可用于生产具有长期抗病毒性能的简单且廉价的涂层,并将为开发针对包括 SARS-CoV-2 在内的广谱病原体的表面涂层开辟道路。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d777/9345348/eee9c86ff201/pone.0272307.g002.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验