Department of Glaucoma, Dr. Shroff's Charity Eye Hospital, Delhi, India.
Indian J Ophthalmol. 2022 Aug;70(8):3016-3020. doi: 10.4103/ijo.IJO_169_22.
To determine the association of primary angle-closure disease (PACD) in patients with retinal vein occlusion (RVO) at a tertiary eye care center in North India.
It is a cross-sectional, observational study. Sixty consecutive patients with retinal vein occlusion within a period of one year from a single tertiary eye care center were enrolled. Detailed history, slit-lamp examination of the anterior segment, intraocular pressure measurement by applanation tonometry, gonioscopy and fundus examination were done. Anterior chamber depth and axial length were also measured.
Among the 60 patients, 29 were males (48.3%) and 31 females (51.6%). Twenty-seven (45%) of them had central retinal vein occlusion (CRVO) and 33 (55%) had branch retinal vein occlusion (BRVO). Forty percent of patients with RVO had PACD. Relative risk of PACD was 1.71 times in patients with CRVO as compared to BRVO. Risk of glaucoma was 49% more in CRVO than BRVO. Probability of PACD was more in patients of RVO who had diabetes and CAD as comorbidity.
The association between PACD and RVO is less known. PACD can be one of the risk factors for the development of RVO. A comprehensive examination and detailed angle evaluation of both of the eyes should be done in all cases of RVO, in addition to investigating for systemic risk factors. However, larger population-based studies would be required to prove it as an independent risk factor.
在印度北部的一家三级眼科中心确定原发性闭角型青光眼(PACG)与视网膜静脉阻塞(RVO)患者之间的关联。
这是一项横断面、观察性研究。在一年的时间内,从一家三级眼科中心连续招募了 60 名视网膜静脉阻塞患者。详细记录病史,进行眼前节裂隙灯检查、压平眼压测量、房角镜检查和眼底检查。还测量了前房深度和眼轴长度。
在 60 名患者中,男性 29 名(48.3%),女性 31 名(51.6%)。27 名(45%)患者为中央视网膜静脉阻塞(CRVO),33 名(55%)为分支视网膜静脉阻塞(BRVO)。40%的 RVO 患者患有 PACG。与 BRVO 相比,CRVO 患者发生 PACG 的相对风险为 1.71 倍。CRVO 比 BRVO 发生青光眼的风险高 49%。同时患有糖尿病和 CAD 等合并症的 RVO 患者发生 PACG 的可能性更高。
PACG 与 RVO 之间的关联知之甚少。PACG 可能是 RVO 发展的危险因素之一。除了调查系统性危险因素外,还应在所有 RVO 患者中进行全面检查和详细的双眼角度评估。然而,需要进行更大的基于人群的研究来证明其为独立的危险因素。