牙科组织工程中释放抗菌剂的支架
Antibacterial agent-releasing scaffolds in dental tissue engineering.
作者信息
Gholami Zahra, Hasanpour Shirin, Sadigh Samira, Johari Sana, Shahveghar Zahra, Ataei Kosar, Javari Eelahe, Amani Mahsa, Javadi Kia Leila, Delir Akbari Zahra, Nazari Zahra, Maleki Dizaj Solmaz, Rezaei Yashar
机构信息
Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
Dental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
出版信息
J Adv Periodontol Implant Dent. 2021 Mar 31;13(1):43-47. doi: 10.34172/japid.2021.003. eCollection 2021.
It seems quite challenging in tissue engineering to synthesize a base material with a range of essential activities, including biocompatibility, nontoxicity, and antimicrobial activities. Various types of materials are synthesized to solve the problem. This study aimed to provide the latest relevant information for practitioners about antibacterial scaffolds in dental tissue engineering. The PubMed search engine was used to review the relevant studies with a combination of the following terms as search queries: tissue engineering, scaffolds, antimicrobial, dentistry, dental stem cells, and oral diseases. It is noteworthy to state that only the terms related to tissue engineering in dentistry were considered. The antimicrobial scaffolds support the local tissue regeneration and prevent adverse inflammatory reactions; however, not all scaffolds have such positive characteristics. To resolve this potential defect, different antimicrobial agents are used during the synthesis process. Innovative methods in guided tissue engineering are actively working towards new ways to control oral and periodontal diseases.
在组织工程中，合成一种具有一系列基本活性（包括生物相容性、无毒性和抗菌活性）的基础材料似乎颇具挑战性。人们合成了各种类型的材料来解决这一问题。本研究旨在为从业者提供有关牙科组织工程中抗菌支架的最新相关信息。使用PubMed搜索引擎，结合以下术语作为搜索查询词来检索相关研究：组织工程、支架、抗菌、牙科、牙干细胞和口腔疾病。值得注意的是，仅考虑与牙科组织工程相关的术语。抗菌支架有助于局部组织再生并预防不良炎症反应；然而，并非所有支架都具有这些积极特性。为了解决这一潜在缺陷，在合成过程中使用了不同的抗菌剂。引导组织工程中的创新方法正积极致力于控制口腔和牙周疾病的新途径。
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