Department of Obstetrics and Gynecology, Helsingborg Central Hospital, Helsingborg, Sweden.
Institution of Clinical Sciences Lund, Lund University, Lund, Sweden.
Acta Obstet Gynecol Scand. 2022 Nov;101(11):1262-1268. doi: 10.1111/aogs.14425. Epub 2022 Aug 3.
Obstetric anal sphincter injuries (OASIS) are severe complications to vaginal births with potentially serious long-term consequences and large impact on quality of life. The aim was to determine risk and protective factors for OASIS.
We performed a retrospective register-based observational study. A cohort of 988 988 singleton term deliveries 2005-2016 in Sweden were included. Data from the Swedish Medical Birth Registry and Statistics Sweden were extracted to identify cases of OASIS and maternal and fetal characteristics. Modified Poisson Regression analyses were performed to assess risk factors.
The rate of OASIS was 3.5% (n = 34 583). Primiparity (adjusted risk ratio [aRR] 3.13, 95% CI 3.05-3.21), vacuum extraction (aRR 2.79, 95% CI 2.73-2.86), forceps (aRR 4.27, 95% CI 3.86-4.72), and high birthweight (aRR 2.61, 95% CI 2.50-2.72) were associated with a significantly increased risk of OASIS. Increasing maternal age and decreasing maternal height also increased the risk of OASIS. Obesity increased the risk of OASIS (aRR 1.04, 95% CI 1.04-1.08), if fetal birthweight was not adjusted for. Smoking (aRR 0.74, 95% CI 0.70-0.79) and low maternal education (aRR 0.87, 95% CI 0.83-0.92) were associated with a decreased frequency of reported OASIS. Previous cesarean section increased the risk of OASIS (aRR 1.41, 95% CI 1.36-1.47).
Primiparity, instrumental delivery, and high birthweight significantly increased the risk of OASIS. Obesity, low height, increasing age, and previous cesarean section also increased the risk whereas smoking and low maternal educational level were associated with a lower OASIS rate.
产科肛门括约肌损伤(OASIS)是阴道分娩的严重并发症,可能导致严重的长期后果,并对生活质量产生重大影响。本研究旨在确定 OASIS 的风险和保护因素。
我们进行了一项回顾性基于登记的观察性研究。纳入了 2005 年至 2016 年瑞典 988988 例单胎足月分娩的队列。从瑞典医学出生登记处和瑞典统计局提取数据,以确定 OASIS 和产妇及胎儿特征的病例。采用修正泊松回归分析评估危险因素。
OASIS 的发生率为 3.5%(n=34583)。初产妇(调整风险比[aRR]3.13,95%可信区间[95%CI]3.05-3.21)、真空吸引(aRR 2.79,95%CI 2.73-2.86)、产钳(aRR 4.27,95%CI 3.86-4.72)和高出生体重(aRR 2.61,95%CI 2.50-2.72)与 OASIS 风险显著增加相关。母亲年龄增加和身高降低也增加了 OASIS 的风险。肥胖(aRR 1.04,95%CI 1.04-1.08)如果未调整胎儿出生体重,则增加了 OASIS 的风险。吸烟(aRR 0.74,95%CI 0.70-0.79)和低母亲教育程度(aRR 0.87,95%CI 0.83-0.92)与报告的 OASIS 发生率降低相关。既往剖宫产增加了 OASIS 的风险(aRR 1.41,95%CI 1.36-1.47)。
初产妇、器械分娩和高出生体重显著增加了 OASIS 的风险。肥胖、身高较低、年龄增加和既往剖宫产也增加了风险,而吸烟和低母亲教育程度与较低的 OASIS 发生率相关。