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基于人工智能设计的电子健康系统在现实世界中的实施,旨在预测并减少老年人的急诊科就诊:实用试验

Real-world Implementation of an eHealth System Based on Artificial Intelligence Designed to Predict and Reduce Emergency Department Visits by Older Adults: Pragmatic Trial.

作者信息

Belmin Joël, Villani Patrick, Gay Mathias, Fabries Stéphane, Havreng-Théry Charlotte, Malvoisin Stéphanie, Denis Fabrice, Veyron Jacques-Henri

机构信息

Hôpital Charles Foix, Assistance Publique-Hôpitaux de Paris, Ivry-sur-Seine, France.

Laboratoire Informatique Médicale et Ingénierie des Connaissances en eSanté (UMRS 1142), Institut National de la Santé et de la Recherche Médicale and Sorbonne Université, Paris, France.

出版信息

J Med Internet Res. 2022 Sep 8;24(9):e40387. doi: 10.2196/40387.

Abstract

BACKGROUND

Frail older people use emergency services extensively, and digital systems that monitor health remotely could be useful in reducing these visits by earlier detection of worsening health conditions.

OBJECTIVE

We aimed to implement a system that produces alerts when the machine learning algorithm identifies a short-term risk for an emergency department (ED) visit and examine health interventions delivered after these alerts and users' experience. This study highlights the feasibility of the general system and its performance in reducing ED visits. It also evaluates the accuracy of alerts' prediction.

METHODS

An uncontrolled multicenter trial was conducted in community-dwelling older adults receiving assistance from home aides (HAs). We implemented an eHealth system that produces an alert for a high risk of ED visits. After each home visit, the HAs completed a questionnaire on participants' functional status, using a smartphone app, and the information was processed in real time by a previously developed machine learning algorithm that identifies patients at risk of an ED visit within 14 days. In case of risk, the eHealth system alerted a coordinating nurse who could then inform the family carer and the patient's nurses or general practitioner. The primary outcomes were the rate of ED visits and the number of deaths after alert-triggered health interventions (ATHIs) and users' experience with the eHealth system; the secondary outcome was the accuracy of the eHealth system in predicting ED visits.

RESULTS

We included 206 patients (mean age 85, SD 8 years; 161/206, 78% women) who received aid from 109 HAs, and the mean follow-up period was 10 months. The HAs monitored 2656 visits, which resulted in 405 alerts. Two ED visits were recorded following 131 alerts with an ATHI (2/131, 1.5%), whereas 36 ED visits were recorded following 274 alerts that did not result in an ATHI (36/274, 13.4%), corresponding to an odds ratio of 0.10 (95% IC 0.02-0.43; P<.001). Five patients died during the study. All had alerts, 4 did not have an ATHI and were hospitalized, and 1 had an ATHI (P=.04). In terms of overall usability, the digital system was easy to use for 90% (98/109) of HAs, and response time was acceptable for 89% (98/109) of them.

CONCLUSIONS

The eHealth system has been successfully implemented, was appreciated by users, and produced relevant alerts. ATHIs were associated with a lower rate of ED visits, suggesting that the eHealth system might be effective in lowering the number of ED visits in this population.

TRIAL REGISTRATION

clinicaltrials.gov NCT05221697; https://clinicaltrials.gov/ct2/show/NCT05221697.

摘要

背景

体弱的老年人广泛使用急诊服务,而能够远程监测健康状况的数字系统可能有助于通过更早发现健康状况恶化来减少此类就诊。

目的

我们旨在实施一种系统,当机器学习算法识别出急诊就诊的短期风险时发出警报,并检查在这些警报发出后提供的健康干预措施以及用户体验。本研究强调了该通用系统的可行性及其在减少急诊就诊方面的表现。它还评估了警报预测的准确性。

方法

在接受家庭护理员(HA)协助的社区居住老年人中进行了一项非对照多中心试验。我们实施了一个电子健康系统,该系统会为急诊就诊的高风险发出警报。每次家访后,家庭护理员使用智能手机应用程序完成一份关于参与者功能状态的问卷,信息由先前开发的机器学习算法实时处理,该算法可识别14天内有急诊就诊风险的患者。如有风险,电子健康系统会提醒一名协调护士,该护士随后可通知家庭护理人员以及患者的护士或全科医生。主要结局是急诊就诊率、警报触发的健康干预措施(ATHI)后的死亡人数以及用户对电子健康系统的体验;次要结局是电子健康系统预测急诊就诊的准确性。

结果

我们纳入了206名患者(平均年龄85岁,标准差8岁;161/206,78%为女性),他们接受了109名家庭护理员的帮助,平均随访期为10个月。家庭护理员监测了2656次家访,共发出405次警报。在131次发出ATHI的警报后记录到2次急诊就诊(2/131,1.5%),而在274次未导致ATHI的警报后记录到36次急诊就诊(36/274,13.4%),对应比值比为0.10(95%置信区间0.02 - 0.43;P <.001)。研究期间有5名患者死亡。所有患者都收到了警报,4名没有接受ATHI并住院,1名接受了ATHI(P = 0.04)。在总体可用性方面,90%(98/109)的家庭护理员认为数字系统易于使用,89%(98/109)的家庭护理员认为响应时间可以接受。

结论

电子健康系统已成功实施,受到用户好评,并发出了相关警报。ATHI与较低的急诊就诊率相关,表明电子健康系统可能有效地减少该人群的急诊就诊次数。

试验注册

clinicaltrials.gov NCT05221697;https://clinicaltrials.gov/ct2/show/NCT05221697

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d363/9501682/685592fad4b8/jmir_v24i9e40387_fig1.jpg

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