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长期随访 MRI 显示颈椎间盘置换术后无邻近节段退变加速。

Long-term follow-up MRI shows no hastening of adjacent segment degeneration following cervical disc arthroplasty.

机构信息

Department of Neurosurgery, Saarland University Medical Center and Saarland University Faculty of Medicine, Homburg-Saar, Germany.

Klinik für Neurochirurgie, Universitätsklinikum des Saarlandes und Medizinische Fakultät der Universität des Saarlandes, Kirrbergerstrasse 100, Gebäude 90.5, 66421, Homburg-Saar, Germany.

出版信息

Sci Rep. 2022 Aug 3;12(1):13318. doi: 10.1038/s41598-022-17652-8.

Abstract

Cervical disc arthroplasty is an established procedure, but studies with data on long-term clinical outcome, reoperation for symptomatic adjacent segment degeneration (sASD), and degenerative changes based on MRI findings are rare. Thus, a file review was performed and patients with complete documentation of neurological status at preoperative, postoperative, 12 month, 3-4 years follow-up including surgical reports for reoperation with a minimum follow-up of 9 years were included. Final follow-up assessment included a physical examination, assessment of pain levels, Odoms criteria, Neck disability index. The degeneration of each cervical segment at preoperative and at final follow-up was assessed using an MRI. Forty-six out of 68 included patients participated, the mean follow-up was 11 (range 9-15) years, at which 71.7% of patients were free of arm pain, 52.2% of patients were free of neck pain, 63% of patients had no sensory dysfunction, and full motor strength was noted in 95.6% of patients. The clinical success rate was 76.1%, the mean NDI was 12%. Overall repeated procedure rate was 17%, the reoperation rate for sASD was 9%, and removal of CDA was performed in 4%. MRI showed progressive degeneration but no significant changes of SDI from preoperative to final follow-up.

摘要

颈椎间盘置换术是一种成熟的手术方法,但关于长期临床结果、症状性相邻节段退变(sASD)再手术以及基于 MRI 发现的退行性改变的研究较少。因此,进行了病历回顾,纳入了术前、术后、12 个月、3-4 年随访时神经状态完整记录的患者,包括再手术的手术报告,随访时间至少为 9 年。最终随访评估包括体格检查、疼痛程度评估、Odoms 标准、颈椎功能障碍指数。使用 MRI 评估每个颈椎节段术前和最终随访时的退变情况。68 例患者中有 46 例参与,平均随访时间为 11 年(范围为 9-15 年),71.7%的患者手臂疼痛消失,52.2%的患者颈部疼痛消失,63%的患者感觉功能正常,95.6%的患者运动功能完全正常。临床成功率为 76.1%,NDI 平均为 12%。总的再次手术率为 17%,sASD 的再手术率为 9%,4%的患者行 CDA 取出术。MRI 显示进行性退变,但 SDI 从术前到最终随访无显著变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea11/9349281/0cc60dfd83dd/41598_2022_17652_Fig1_HTML.jpg

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