Leidner Andrew J, Lee Carla E, Tippins Ashley, Messonnier Mark L, Stevenson John M
Immunization Services Division, NCIRD, CDC.
Global Immunization Division, GID, CDC.
J Public Health (Bangkok). 2020 Mar 22;29(6):1253-1260. doi: 10.1007/s10389-020-01207-0.
Evaluate different non-continuous temperature monitoring practices for detection of out-of-range temperatures (above or below the recommended temperature range of 2-8°C for refrigeration units), which are called excursions, within vaccine storage units.
Simulations based on temperature data collected by 243 digital data loggers operated in vaccine storage units at health care providers who participated in a CDC-sponsored continuous temperature monitoring pilot project, from 2012 to 2015. In the primary analysis, we evaluate: (1) twice-daily current temperature readings without minimum and maximum readings (min/max), (2) twice-daily current temperature readings with once-daily min/max, and (3) twice-daily current temperature readings with twice-daily min/max.
Recording current temperature twice-daily without min/max resulted in the detection of 4.8-6.4% of the total number of temperature excursions. When min/max readings were introduced, the percentage of detected temperature excursions increased to 27.8-96.6% with once-daily min/max and to 34.8-96.7% with twice-daily min/max.
Including min/max readings improves the ability of a temperature monitoring practice to detect temperature excursions. No combination of the non-continuous temperature monitoring practices were able to consistently detect all simulated temperature excursions.
评估不同的非连续温度监测方法，以检测疫苗储存单元内超出温度范围（冷藏单元推荐温度范围为2 - 8°C，超出此范围称为温度偏移）的情况。
基于2012年至2015年参与美国疾病控制与预防中心（CDC）赞助的连续温度监测试点项目的医疗服务提供者的疫苗储存单元中运行的243个数字数据记录器收集的温度数据进行模拟。在主要分析中，我们评估：（1）每日两次的当前温度读数，无最低和最高读数（min/max）；（2）每日两次的当前温度读数，每日一次的min/max；（3）每日两次的当前温度读数，每日两次的min/max。
每日两次记录当前温度且无min/max，能检测到的温度偏移总数占比为4.8 - 6.4%。当引入min/max读数时，每日一次min/max检测到的温度偏移百分比增至27.8 - 96.6%，每日两次min/max则增至34.8 - 96.7%。
包含min/max读数可提高温度监测方法检测温度偏移的能力。非连续温度监测方法的任何组合都无法始终检测到所有模拟的温度偏移。
