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复发性阿弗他口炎影响生活质量。一项病例对照研究。

Recurrent Aphthous Stomatitis Affects Quality of Life. A Case-Control Study.

作者信息

Rivera César, Muñoz-Pastén Mariagrazia, Núñez-Muñoz Esteban, Hernández-Olivos Romina

机构信息

Department of Basic Biomedical Sciences, Faculty of Health Sciences, Universidad de Talca, Talca, Chile.

Department of Stomatology, Faculty of Dentistry, Universidad de Talca, Talca, Chile.

出版信息

Clin Cosmet Investig Dent. 2022 Jul 26;14:217-223. doi: 10.2147/CCIDE.S369481. eCollection 2022.

DOI:10.2147/CCIDE.S369481
PMID:35923688
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9341334/
Abstract

AIM

To determine the impact of recurrent aphthous stomatitis on quality of life related to oral health, and then to determine the relationship between the observed impact and lesions characteristics.

METHODS

In this prospective case-control study (n=62), patients were divided into a healthy group (people with no history of ulcers) and recurrent aphthous stomatitis (people who had an active ulcer at study entry). The latter were also evaluated when the lesion disappeared (remission stage). We record the quality of life in all groups using the impact profile of oral health in its abbreviated Spanish version (OHIP-14SP). Finally, we correlate the clinical characteristics of the lesions with the levels of quality of life.

RESULTS

All the lesions were of the minor morphological type. Most of the lesions were located on the lining mucosa, primarily on the lips. Patients report a lower quality of life during ulcer episodes compared to ulcer-free periods, and this impact is positively related to the number and size of lesions.

CONCLUSION

We concluded that recurrent aphthous stomatitis increased the negative effects of oral health on the quality of life of patients. The number and size of ulcers are responsible for this impact. Our results suggest that, if intervened locally, general relief of the condition could be achieved.

摘要

目的

确定复发性阿弗他口炎对口腔健康相关生活质量的影响,进而确定观察到的影响与病变特征之间的关系。

方法

在这项前瞻性病例对照研究(n = 62)中,患者被分为健康组(无溃疡病史者)和复发性阿弗他口炎组(研究开始时患有活动性溃疡者)。后者在病变消失时(缓解期)也进行了评估。我们使用口腔健康影响简表的西班牙语缩写版(OHIP - 14SP)记录所有组的生活质量。最后,我们将病变的临床特征与生活质量水平进行关联。

结果

所有病变均为轻度形态类型。大多数病变位于黏膜内衬,主要在唇部。与无溃疡期相比,患者在溃疡发作期间报告生活质量较低,且这种影响与病变的数量和大小呈正相关。

结论

我们得出结论,复发性阿弗他口炎增加了口腔健康对患者生活质量的负面影响。溃疡的数量和大小是造成这种影响的原因。我们的结果表明,如果进行局部干预,可以实现病情的总体缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37ac/9341334/37878ff8034d/CCIDE-14-217-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37ac/9341334/37878ff8034d/CCIDE-14-217-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37ac/9341334/37878ff8034d/CCIDE-14-217-g0001.jpg

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