Zhang Tongqiang, Zheng Jiafeng, Wang Hongbo, Xu Yongsheng, Ning Jing, Cai Chunquan
Department of Respiratory, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Tianjin, China.
Tianjin Institute of Pediatrics, Tianjin Key Laboratory of Birth Defects for Prevention and Treatment, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Tianjin, China.
Front Pediatr. 2022 Jul 18;10:959218. doi: 10.3389/fped.2022.959218. eCollection 2022.
Mycoplasma pneumoniae (MP) is a common pathogen of lower respiratory tract infection in children and adolescents. Some patients with MP infection are self-limiting, while with the increase of severe or refractory Mycoplasma pneumoniae pneumonia (MPP) in recent years, there is a great increase in reports of thromboembolism in multiple organs, including lung, brain, spleen, and peripheral arteries. Cardiac multiple thrombi and pulmonary embolism associated with MP infection have not been reported. The most effective treatment option for cardiac thrombus was surgical resection for fear of thrombus detachment and causing new thromboembolism. Herein, we present a patient with cardiac multiple thrombi and pulmonary embolism in MPP for the first time. In our case, the child recovered after conservative medical treatment, which provides a therapeutic option for children with cardiac multiple thrombi.
肺炎支原体(MP)是儿童和青少年下呼吸道感染的常见病原体。一些MP感染患者具有自限性,而近年来随着重症或难治性肺炎支原体肺炎(MPP)病例增多,包括肺、脑、脾及外周动脉在内的多器官血栓栓塞的报道大幅增加。与MP感染相关的心脏多发性血栓和肺栓塞尚未见报道。由于担心血栓脱落并导致新的血栓栓塞,心脏血栓最有效的治疗选择是手术切除。在此,我们首次报告一名患有MPP并伴有心脏多发性血栓和肺栓塞的患者。在我们的病例中,该患儿经保守药物治疗后康复,这为患有心脏多发性血栓的儿童提供了一种治疗选择。