两项双氯芬酸治疗骨关节炎的试验。
Two trials of diflunisal in osteoarthritis.
作者信息
Grayson M F
出版信息
Curr Med Res Opin. 1978;5(7):567-71. doi: 10.1185/03007997809109003.
PMID:359252
Abstract
Two double-blind inter-group trials were carried out in which diflunisal was compared for 12 weeks against aspirin in 30 patients with osteoarthritis of knees or hips, and against naproxen for 8 weeks in 20 patients with osteoarthritic knees. Diflunisal appeared to be somewhat better than aspirin in terms of both effectiveness and tolerance, whilst it was similar in both repects to naproxen.
摘要
进行了两项双盲组间试验，其中一项是在30名膝部或髋部骨关节炎患者中，将双氟芬酸与阿司匹林比较12周；另一项是在20名膝部骨关节炎患者中，将双氟芬酸与萘普生比较8周。在有效性和耐受性方面，双氟芬酸似乎比阿司匹林略好，而在这两方面与萘普生相似。
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