Electroanalytical Chemistry Laboratory, Faculty of Chemistry, University of Guilan, Namjoo Street, P.O. Box: 1914-41335, Rasht, Iran.
Electroanalytical Chemistry Laboratory, Faculty of Chemistry, University of Guilan, Namjoo Street, P.O. Box: 1914-41335, Rasht, Iran.
Food Chem. 2022 Dec 15;397:133829. doi: 10.1016/j.foodchem.2022.133829. Epub 2022 Jul 30.
Aflatoxin B is a potent liver toxin and easily accumulated in foodstuff and environment via the food chain, subjecting high hazards to human health. Rapid initial diagnosis is one of the most impressive monitoring procedures to overcome the potential hazards. Nevertheless, the classical approaches confront many limitations, like low specificity and sensitivity and complicated procedures. Herein, a photo-electrochemical aptasensor based on sensitized poly(dopamine)@functionalized multiwall carbon nanotube/titanium dioxide (PDA@f-MWCNTs/TiO NTs) was designed to detect aflatoxin B in real samples (e.g. groundnut and milk). The mentioned label-free biosensing platform not only needed simple operations but also presented outstanding reusability, storage stability, reproducibility, and specificity simultaneously. This suggested strategy could sensitively and selectively detect aflatoxin B with dynamic range of 0.005-50 ng/mL and a low limit of detection 1 pg/mL. This procedure could provide the bright prospect for detection of aflatoxin B residues in foodstuff.
黄曲霉毒素 B 是一种很强的肝脏毒素，很容易通过食物链在食物和环境中积累，对人类健康构成高危害。快速的初步诊断是克服潜在危害的最令人印象深刻的监测程序之一。然而，经典方法面临许多限制，如特异性和灵敏度低以及操作复杂。在此，设计了一种基于敏化聚多巴胺@功能化多壁碳纳米管/二氧化钛（PDA@f-MWCNTs/TiO2NTs）的光电化学适体传感器，用于检测实际样品（如花生和牛奶）中的黄曲霉毒素 B。所述无标记生物传感平台不仅需要简单的操作，而且同时具有出色的可重复使用性、储存稳定性、重现性和特异性。该策略可以灵敏和选择性地检测黄曲霉毒素 B，其动态范围为 0.005-50ng/mL，检测限低至 1pg/mL。该方法为检测食品中的黄曲霉毒素 B 残留提供了广阔的前景。
