Epasinghege Dona Nirodha, Graham Jinko
Department of Statistics and Actuarial Science, Simon Fraser University, Burnaby V5A 1S6, Canada.
Data Brief. 2022 May 26;42:108311. doi: 10.1016/j.dib.2022.108311. eCollection 2022 Jun.
We present simulated exome-sequencing data for 150 families from a North American admixed population, ascertained to contain at least four members affected with lymphoid cancer. These data include information on the ascertained families as well as single-nucleotide variants on the exome of affected family members. We provide a brief overview of the simulation steps and links to the associated software scripts. The resulting data are useful to identify genomic patterns and disease inheritance in families with multiple disease-affected members.
我们展示了来自北美混合人群的150个家庭的模拟外显子组测序数据,这些家庭经确定至少有四名成员患有淋巴癌。这些数据包括已确定家庭的相关信息以及受影响家庭成员外显子组上的单核苷酸变异。我们简要概述了模拟步骤以及相关软件脚本的链接。所得数据有助于识别有多名患病成员的家庭中的基因组模式和疾病遗传情况。