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阴茎平滑肌肉瘤:一例报告及重新评估

Leiomyosarcoma of the Penis: A Case Report and Re-Appraisal.

作者信息

Ajmal Zainub, Khan Abdul Moiz, Zahra Fatima Tuz, McCarthy Lezah, O'Malley Rebecca, Mehdi Syed

机构信息

Albany Medical Center, New York.

Stratton Veterans Affairs Medical Center, Albany, New York.

出版信息

Fed Pract. 2022 May;39(Suppl 2):S58-S61. doi: 10.12788/fp.0232. Epub 2022 May 13.

DOI:10.12788/fp.0232
PMID:35929007
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9346577/
Abstract

BACKGROUND

Penile leiomyosarcoma arises from smooth muscles, which can be from dartos fascia, erector pili in the skin covering the shaft, or from tunica media of the superficial vessels and cavernosa. We describe presentation, treatment options, and recurrence pattern of this rare malignancy.

CASE PRESENTATION

We present a case of penile leiomyosarcoma in a 70-year-old patient who presented to the urology clinic with 1-year history of a slowly enlarging penile mass associated with phimosis.

CONCLUSIONS

Prognosis of penile LMS is difficult to ascertain because reported cases are rare. Penile leiomyosarcoma can be classified as superficial or deep based on tumor relation to tunica albuginea. Deep tumors (> 3 cm), high-grade lesions, and tumors with involvement of corpora cavernosa, tend to spread locally and metastasize to distant areas and require more radical surgery with or without postoperative radiation therapy. In contrast, superficial lesions can be treated with local excision only.

摘要

背景

阴茎平滑肌肉瘤起源于平滑肌,其可来源于肉膜、阴茎体皮肤的竖毛肌,或浅表血管及海绵体的中膜。我们描述了这种罕见恶性肿瘤的临床表现、治疗选择及复发模式。

病例报告

我们报告一例70岁阴茎平滑肌肉瘤患者,该患者因阴茎肿物缓慢增大伴包茎1年就诊于泌尿外科门诊。

结论

阴茎平滑肌肉瘤的预后难以确定,因为报道的病例较少。阴茎平滑肌肉瘤可根据肿瘤与白膜的关系分为浅表型或深部型。深部肿瘤(>3cm)、高级别病变以及累及海绵体的肿瘤,往往会局部扩散并转移至远处,需要进行更彻底的手术,术后可联合或不联合放疗。相比之下,浅表病变仅行局部切除即可。

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Incidence of penile cancer worldwide: systematic review and meta-analysis.全球阴茎癌发病率:系统评价与荟萃分析。
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Leiomyosarcoma of the larynx as a local relapse of squamous cell carcinoma--report of an unusual case.喉平滑肌肉瘤作为鳞状细胞癌的局部复发——一个不常见病例的报告。
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