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农村巴西人群中甘油三酯-葡萄糖指数与胰岛素抵抗的关系。

Insulin resistance by the triglyceride-glucose index in a rural Brazilian population.

机构信息

Programa de Pós-graduação em Saúde Pública, Universidade Federal do Espírito Santo (UFES), Vitória, ES, Brasil,

Programa de Pós-graduação em Saúde Pública, Universidade Federal do Espírito Santo (UFES), Vitória, ES, Brasil.

出版信息

Arch Endocrinol Metab. 2022 Nov 17;66(6):848-855. doi: 10.20945/2359-3997000000509. Epub 2022 Aug 4.

Abstract

OBJECTIVE

The aim of this study was to estimate the prevalence of insulin resistance (IR) in a rural population in Brazil, to verify its association with sociodemographic, labor, lifestyle, and health factors.

SUBJECTS AND METHODS

This is a cross-sectional study with 790 farmers in the state of Espírito Santo/Brazil. Triglyceride-glucose (TyG) was calculated and a cut-off point of Ln 4.52 was used. A hierarchical logistic regression for the association of insulin resistance with sociodemographic, labor, lifestyle and health variables of farmers living in Espírito Santo was performed.

RESULTS

The prevalence of insulin resistance was 33.7% (n = 266), and the association with insulin resistance was found in the age group 31 to 40 years of age (OR = 1.85; 95% CI 1.19-2.87); in smokers or former smokers (OR = 1.63; 95% CI 1.08-2.48) and overweight (OR = 3.06; 95% CI 2.22-4.23).

CONCLUSION

The prevalence of insulin resistance was high in a rural population of Brazil, and was mainly associated with age, smoking and obesity. The use of TyG as an instrument for assessing the health of individuals living in areas where access to health services is difficult, such as rural areas, can represent an important advance in terms of health promotion, protection and recovery. In addition, by identifying the risk factors associated with IR, as well as their consequences, a more adequate scheme for the prevention and treatment of these comorbidities can be defined.

摘要

目的

本研究旨在评估巴西农村人群中胰岛素抵抗(IR)的患病率,并验证其与社会人口学、劳动、生活方式和健康因素的相关性。

方法

这是一项在巴西圣埃斯皮里图州进行的横断面研究,共纳入了 790 名农民。计算甘油三酯-葡萄糖(TyG)并使用 Ln 4.52 作为截断点。对生活在圣埃斯皮里图州的农民的胰岛素抵抗与社会人口学、劳动、生活方式和健康变量的相关性进行了分层逻辑回归分析。

结果

胰岛素抵抗的患病率为 33.7%(n=266),与胰岛素抵抗相关的因素包括 31-40 岁年龄组(OR=1.85;95%CI 1.19-2.87);吸烟者或曾经吸烟者(OR=1.63;95%CI 1.08-2.48)和超重者(OR=3.06;95%CI 2.22-4.23)。

结论

巴西农村人群的胰岛素抵抗患病率较高,主要与年龄、吸烟和肥胖有关。使用 TyG 作为评估难以获得医疗服务地区(如农村地区)个体健康状况的工具,可以在促进、保护和恢复健康方面取得重要进展。此外,通过识别与 IR 相关的风险因素及其后果,可以制定更合适的预防和治疗这些合并症的方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc2e/10118758/5e082f80a09f/2359-4292-aem-66-06-0848-gf01.jpg

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