Am J Vet Res. 2022 Aug 9;83(10):ajvr.22.05.0077. doi: 10.2460/ajvr.22.05.0077.
To identify and characterize the gross and histological lesions associated with air pollution in the lungs of dogs from various locations in Trinidad.
56 fresh lungs were obtained from already euthanized adult dogs collected from different locations in Trinidad at the Trinidad and Tobago Society for the Prevention of Cruelty to Animals.
Lung specimens were examined grossly and tissue samples were taken for routine histologic examination.
Histological examination showed that 51.8% of the dogs had evidence of anthracosis. Dogs with anthracosis had greater median lesion scores compared to dogs without anthracosis (P = .022). There was no association between the presence of anthracosis and any other lesion in this study (P > .05).
There was evidence that dogs with anthracosis had a greater degree of nonspecific lung histologic lesions. Using the dog as a sentinel model for human exposure in Trinidad, our findings indicate that environmental air pollution may also have an effect on the respiratory health of the human population. It is important for the public to be aware of air pollution, and the government of Trinidad and Tobago should develop an intervention protocol along with veterinary and human medical epidemiologists to reduce air pollution in the country.
确定和描述特立尼达不同地区狗的肺部因空气污染而导致的大体和组织学病变。
从特立尼达和多巴哥防止虐待动物协会已处死的成年狗中获得了 56 个新鲜肺脏，这些狗分别来自特立尼达的不同地区。
对肺脏标本进行大体检查，并采集组织样本进行常规组织学检查。
组织学检查显示，51.8%的狗有炭末沉着的证据。有炭末沉着的狗的病变评分中位数高于没有炭末沉着的狗（P=.022）。在本研究中，炭末沉着的存在与任何其他病变之间均无关联（P＞.05）。
有证据表明，有炭末沉着的狗具有更严重的非特异性肺部组织学病变。使用狗作为特立尼达的人类暴露哨兵模型，我们的研究结果表明，环境空气污染可能也会影响人类的呼吸系统健康。公众需要了解空气污染问题，特立尼达和多巴哥政府应该与兽医和人类医学流行病学家一起制定干预方案，以减少该国的空气污染。
