Shah Rucha, Thomas Raison, Triveni M G, Kumar Baron Tarun
Reader, Department of Periodontics, Bapuji Dental College and Hospital,Karnataka, India.
Professor, Department of Periodontics, Bapuji Dental College and Hospital, Karnataka, India.
Compend Contin Educ Dent. 2022 Jun;43(6):336-345; quiz 346.
Platelet concentrates have seen significant advancement in the field of biological surgical wound additives. The focus is now on second-generation platelet concentrates, which are completely autologous with no external additives. Unlike other platelet concentrates, liquid or injectable platelet-rich fibrin (i-PRF) is the only one that is obtained in a liquid form. This property widens the horizons for its application to virtually any medical field, including many uses in dentistry. Over the past several years, studies have proposed different variations of i-PRF, such as changes to the protocol by varying centrifugation time, g-force, and other factors. The liquid or injectable form of PRF also allows for other modifications, such as the addition of various biomaterials. This article reviews the current evidence and advancements regarding i-PRF and its potential future applications.
血小板浓缩物在生物外科伤口添加剂领域取得了显著进展。目前的重点是第二代血小板浓缩物，它们完全是自体的，没有外部添加剂。与其他血小板浓缩物不同，液体或可注射的富血小板纤维蛋白（i-PRF）是唯一以液体形式获得的。这一特性拓宽了其在几乎任何医学领域的应用范围，包括在牙科的许多用途。在过去几年中，研究提出了i-PRF的不同变体，例如通过改变离心时间、重力和其他因素来改变方案。PRF的液体或可注射形式还允许进行其他修饰，例如添加各种生物材料。本文综述了关于i-PRF及其潜在未来应用的当前证据和进展。
