State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.
Department of Plant Biochemistry, Centre for Plant Molecular Biology (ZMBP), Eberhard Karls University, D-72076 Tübingen, Germany.
Trends Microbiol. 2022 Oct;30(10):915-917. doi: 10.1016/j.tim.2022.07.009. Epub 2022 Aug 2.
Despite extensive understanding of antiviral RNAi in plants, whether and how natural variation in components of RNAi contributes to antiviral immunity remains obscure. Liu et al. recently identified novel positive and negative antiviral RNAi regulators, supporting RNAi's principal role in the dynamic virus-host coevolution in natural ecosystems.
尽管人们对植物中的抗病毒 RNAi 有了广泛的了解,但自然变异的 RNAi 成分是否以及如何有助于抗病毒免疫仍然不清楚。Liu 等人最近鉴定了新的正向和负向抗病毒 RNAi 调节剂,支持了 RNAi 在自然生态系统中病毒-宿主共同进化的动态过程中的主要作用。