体力活动减弱了中国农村人口家庭空气污染与健康相关生活质量之间的关联：河南农村队列研究。
Physical activity attenuates the association between household air pollution and health-related quality of life in Chinese rural population: the Henan Rural Cohort Study.
作者信息
Zhang Caiyun, Liu Xiaotian, Kang Ning, Hou Xiaoyu, Liao Wei, Yuchi Yinghao, Ding Zhongao, Baheti Bota, Chang Gaohua, Mao Zhenxing, Huo Wenqian, Hou Jian, Wang Chongjian
机构信息
Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, 100 Kexue Avenue, Zhengzhou, 450001, Henan, People's Republic of China.
Department of Occupational and Environmental Health Sciences, College of Public Health, Zhengzhou University, 100 Kexue Avenue, Zhengzhou, 450001, Henan, People's Republic of China.
出版信息
Qual Life Res. 2022 Nov;31(11):3165-3175. doi: 10.1007/s11136-022-03195-y. Epub 2022 Aug 7.
BACKGROUND AND PURPOSE
Limited research focused on the association between household air pollution (HAP) and health-related quality of life (HRQoL). This study aimed to investigate the association of HAP with HRQoL and the effect modification of physical activity.
METHOD
A total of 16,761 eligible participants were derived from the Henan Rural Cohort Study. Based on structured questionnaires, HAP was assessed by fuel type, cooking duration and kitchen ventilation; HRQoL was measured with utility index and VAS score from the European Quality of Life Five Dimension Five Level Scale (EQ-5D-5L); physical activity was assessed by the International Physical Activity Questionnaire. Generalized linear models and tobit regression models were utilized to explore the relationship of HAP with HRQoL. Further sensitivity analyses were conducted using structural equation models.
RESULTS
Compared with those who cooked with clean fuels, short-duration, or good kitchen ventilation, participants who cooked with solid fuels, long-duration, and poor ventilation had lower utility index and VAS score (All P < 0.001). The decrease in utility index for solid fuel users vs. clean fuel users were 0.06 [95%confidence interval (CI) 003, 0.08], 0.03 (95%CI 0.01, 0.04) and 0.02 (95%CI 0.01, 0.04) in low, moderate and high physical activity group, respectively, which decreased with physical activity levels (P < 0.05). Similar results were observed in associations of kitchen ventilation with utility index and VAS score.
CONCLUSION
HAP negatively associated with HRQoL in rural population, and potential intervention aimed at maintaining adequate physical activity.
TRAIL REGISTRATION
The Henan Rural Cohort Study has been registered at Chinese Clinical Trial Register (Registration number: ChiCTR-OOC-15006699). Date of registration: 06 July, 2015. http://www.chictr.org.cn/showproj.aspx?proj=11375 .
背景与目的
针对家庭空气污染（HAP）与健康相关生活质量（HRQoL）之间关联的研究有限。本研究旨在调查HAP与HRQoL之间的关联以及身体活动的效应修正作用。
方法
共有16761名符合条件的参与者来自河南农村队列研究。基于结构化问卷，通过燃料类型、烹饪时长和厨房通风情况评估HAP；使用欧洲生活质量五维度五级量表（EQ-5D-5L）的效用指数和视觉模拟评分（VAS）来测量HRQoL；通过国际体力活动问卷评估身体活动。采用广义线性模型和托比特回归模型探讨HAP与HRQoL之间的关系。使用结构方程模型进行进一步的敏感性分析。
结果
与使用清洁燃料、烹饪时间短或厨房通风良好的参与者相比，使用固体燃料、烹饪时间长且通风不良的参与者效用指数和VAS评分更低（所有P<0.001）。在低、中、高身体活动组中，固体燃料使用者与清洁燃料使用者相比，效用指数的下降分别为0.06[95%置信区间（CI）0.03，0.08]、0.03（95%CI 0.01，0.04）和0.02（95%CI 0.01，0.04），且随身体活动水平降低（P<0.05）。在厨房通风与效用指数和VAS评分的关联中也观察到类似结果。
结论
农村人群中HAP与HRQoL呈负相关，潜在干预措施旨在保持充足的身体活动。
试验注册
河南农村队列研究已在中国临床试验注册中心注册（注册号：ChiCTR-OOC-15006699）。注册日期：2015年7月6日。http://www.chictr.org.cn/showproj.aspx?proj=11375 。
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