Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, Henan, PR China.
Department of Economics, Business School, Zhengzhou University, Zhengzhou, Henan, PR China.
Eur J Public Health. 2021 Jul 13;31(3):547-553. doi: 10.1093/eurpub/ckaa247.
Previous reports about health-related quality of life (HRQoL) of type 2 diabetes mellitus (T2DM) concentrated on general patients rather than patients in rural areas with poor infrastructure and limited resources. Thus, the aims of this study were to evaluate the HRQoL of diabetics in the countryside and explore its influencing factors.
A total of 23 053 participants aged from 18 to 79 years were drawn from the Henan Rural Cohort Study for this cross-sectional study. The HRQoL of participants were assessed by utility index and VAS-score of European Quality of Life Five Dimension Five Level Scale (EQ-5D-5L) instrument. Binary logistic regression, generalized linear and tobit regression models were used to estimate the potential influencing factors on HRQoL.
This study (23 053 participants) included 2231 T2DM patients with a crude prevalence of 9.68%. The utility index and VAS-score in health group were 0.96 ± 0.10 and 78.85 ± 14.53, while in T2DM group were 0.93 ± 0.15 and 74.09 ± 16.09, respectively. In total, most diabetics reported problem about pain/discomfort dimension. Being old, poverty, low physical activity, and with comorbidities was negatively related to HRQoL of diabetics, while high educational level was positively related to HRQoL.
HRQoL of rural T2DM patients depended on several sociodemographic factors. More attention should be paid to diabetics with poor socioeconomic status in rural areas.
The Henan Rural Cohort Study has been registered at Chinese Clinical Trial Register (Registration number: ChiCTR-OOC-15006699) http://www.chictr.org.cn/showproj.aspx?proj=11375.
以往关于 2 型糖尿病（T2DM）患者健康相关生活质量（HRQoL）的报告主要集中在一般患者身上，而不是基础设施差、资源有限的农村地区的患者。因此，本研究旨在评估农村地区糖尿病患者的 HRQoL，并探讨其影响因素。
本横断面研究共纳入来自河南农村队列研究的 23053 名年龄在 18 至 79 岁的参与者。采用欧洲生活质量五维五水平量表（EQ-5D-5L）工具的效用指数和 VAS 评分评估参与者的 HRQoL。采用二元逻辑回归、广义线性和 Tobit 回归模型来估计对 HRQoL 有潜在影响的因素。
本研究（23053 名参与者）包括 2231 名 T2DM 患者，粗患病率为 9.68%。健康组的效用指数和 VAS 评分分别为 0.96±0.10 和 78.85±14.53，而 T2DM 组分别为 0.93±0.15 和 74.09±16.09。总体而言，大多数糖尿病患者报告存在疼痛/不适维度的问题。年龄较大、贫困、低身体活动水平和合并症与糖尿病患者的 HRQoL 呈负相关，而高教育水平与 HRQoL 呈正相关。
农村 T2DM 患者的 HRQoL 取决于多种社会人口因素。应更加关注农村地区社会经济状况较差的糖尿病患者。
河南农村队列研究已在中国临床试验注册中心（注册号：ChiCTR-OOC-15006699）注册，网址为：http://www.chictr.org.cn/showproj.aspx?proj=11375。
