Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St Louis, MO, USA.
Carniol Plastic Surgery, Summit, NJ, USA; Joint Bachelor's/M.D. Program, Seton Hall University, 33 Overlook Road, Suite 401, Summit, South Orange, NJ 070901, USA.
Facial Plast Surg Clin North Am. 2022 Aug;30(3):389-397. doi: 10.1016/j.fsc.2022.03.012.
Microneedling, also referred to as percutaneous collagen induction therapy, uses small needles to create mechanical injury to the skin, stimulating the wound-healing cascade and new collagen formation. Compared with other skin resurfacing techniques, microneedling preserves the epidermis and is nonablative, therefore reducing inflammation, downtime, and risk of dyspigmentation. In addition to increasing collagen production in fibroblasts, microneedling also helps normalize cell function of keratinocytes and melanocytes and can be used to increase absorption of topical medications, growth factors, or deliver radiofrequency directly to the dermis. The benefits of microneedling, associated procedures, indications for use, technical considerations, and potential complications are discussed.
微针，也称为经皮胶原诱导治疗，使用小针在皮肤造成机械性损伤，刺激创伤愈合级联反应和新的胶原蛋白形成。与其他皮肤表面重建技术相比，微针保留了表皮，是非消融性的，因此减少了炎症、停机时间和色素沉着异常的风险。除了增加成纤维细胞中的胶原蛋白产生外，微针还有助于角质形成细胞和黑素细胞的正常细胞功能，可用于增加局部药物、生长因子的吸收，或直接将射频传递到真皮。讨论了微针的益处、相关程序、适应证、技术注意事项和潜在并发症。
