Fanian Ferial, Casabona Gabriela, Bartoletti Emanuele, Cartier Hugues, Landau Marina, Galadari Hassan, Bageorgou Fotini, Ogilvie Alexandra, Theodorakopoulou Elina, Arteaga Ariana, Gokalp Hilal, Pisal Philippe Hamida, Lopez Ingrid Gerhke, Rucinski Gabriel, Chebbah Myriam, Le Clanche Solenn, Varlet Alice-Anaïs, Sukmanskaya Natalia, Issa Hanane, Philippon Valerie, Stratigos Alexander
Scientific Department, Laboratoires FILLMED, Paris, France.
Ocean Clinic Marbella, Malaga, Spain.
J Cosmet Dermatol. 2025 Feb;24(2):e16623. doi: 10.1111/jocd.16623. Epub 2025 Jan 22.
NCTF135HA, a versatile polyrevitalizing solution, is a potent agent for enhancing skin quality, radiance, moisture, vitality, and diminishing fine wrinkles caused by aging factors. Data demonstrate a divergence in its application from skin quality enhancement to treatment of vitiligo lesions. To know more precisely about the protocol of use among providers, alone or in combination with other procedures, we performed an international survey.
A Steering Committee of dermatologists, aesthetic surgeons, and physicians developed a 32-question questionnaire based on a literature review. Hosted online from January to March 2024, it targeted healthcare professionals experienced in polyrevitalization. Responses were analyzed anonymously and reported descriptively.
Practitioners adopt a balanced approach: half of their patients receiving classic Polyrevitalization (NCTF135HA alone) and the other half undergoing combination therapy (NCTF135HA with another aesthetic procedure). Most administer NCTF135HA across multiple sessions, typically three (39.7%). In combination therapy, 55.5% of practitioners use NCTF135HA for medical purposes, targeting Melasma (53.1%) and Rosacea (45.0%) for instance. Aesthetic use is prevalent, with 94.2% employing NCTF135HA for skin wrinkles (79.9%), and refreshment, rejuvenation, and hydration (73.4%). Combining NCTF135HA with hyaluronic acid (71.2%) and botulinum toxin (49.1%) is common, alongside microneedling (50.2%), peelings (32.4%), and fractional radiofrequency (25.6%).
Our survey showed a homogenous distribution of NCTF135HA utilization, indicating a consensus on its application across diverse demographics. This consistency highlights its widespread acknowledgment and efficacy in various aesthetic and clinical settings. Limitations include a large respondent group from Mexico and many respondents with less than 10 years of experience.
NCTF135HA是一种多功能的复颜溶液，是增强皮肤质量、光泽、水分、活力以及减少由衰老因素引起的细纹的有效制剂。数据表明其在应用方面存在差异，从增强皮肤质量到治疗白癜风皮损。为了更精确地了解医疗服务提供者单独使用或与其他程序联合使用时的使用方案，我们开展了一项国际调查。
一个由皮肤科医生、美容外科医生和内科医生组成的指导委员会在文献综述的基础上制定了一份包含32个问题的问卷。该问卷于2024年1月至3月在网上进行，目标是有复颜经验的医疗保健专业人员。对回复进行匿名分析并进行描述性报告。
从业者采用一种平衡的方法：他们一半的患者接受经典复颜治疗（仅使用NCTF135HA），另一半接受联合治疗（NCTF135HA与另一种美容程序联合）。大多数人在多个疗程中使用NCTF135HA，通常为三个疗程（39.7%）。在联合治疗中，55.5%的从业者将NCTF135HA用于医疗目的，例如针对黄褐斑（53.1%）和酒渣鼻（45.0%）。美容用途很普遍，94.2%的人将NCTF135HA用于改善皮肤皱纹（79.9%）以及焕肤、嫩肤和保湿（73.4%）。NCTF135HA与透明质酸（71.2%）和肉毒杆菌毒素（49.1%）联合使用很常见，同时也与微针疗法（50.2%）、化学剥脱术（32.4%）和分次射频（25.6%）联合使用。
我们的调查显示NCTF135HA的使用分布均匀，表明在不同人群中对其应用达成了共识。这种一致性突出了其在各种美容和临床环境中得到广泛认可和疗效。局限性包括来自墨西哥的应答者群体较大以及许多应答者经验不足10年。
