Grünberger J, Linzmayer L, Cepko H, Saletu B
Arzneimittelforschung. 1987 Mar;37(3):357-60.
In a double-blind placebo-controlled study 100 mg zotepine (neuroleptic) were administered to 15 young healthy volunteers; another 15 volunteers received 200 mg moclobemide (Ro 11-1163) (MAO-inhibitor). At the certain days of investigation the light-evoked pupillary reactions were recorded prior to and 2, 4, 6, and 8 h after medication. Using the dynamic pupillometric method it was possible to differentiate between zotepine and moclobemide in view of autonomous activation.
在一项双盲安慰剂对照研究中，给15名年轻健康志愿者服用100毫克佐替平（抗精神病药）；另外15名志愿者服用200毫克吗氯贝胺（Ro 11 - 1163）（单胺氧化酶抑制剂）。在研究的特定日子，于用药前以及用药后2、4、6和8小时记录光诱发的瞳孔反应。使用动态瞳孔测量法，鉴于自主激活作用，可以区分佐替平和吗氯贝胺。
