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母亲残疾与新生儿结局的关系

Neonatal Outcomes of Mothers With a Disability.

机构信息

Departments of Health and Society.

Dalla Lana School of Public Health.

出版信息

Pediatrics. 2022 Sep 1;150(3). doi: 10.1542/peds.2021-055318.

DOI:10.1542/peds.2021-055318
PMID:35934737
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9694113/
Abstract

OBJECTIVES

To assess the risk of neonatal complications among women with a disability.

METHODS

This population-based cohort study comprised all hospital singleton livebirths in Ontario, Canada from 2003 to 2018. Newborns of women with a physical (N = 144 187), sensory (N = 44 988), intellectual or developmental (N = 2207), or ≥2 disabilities (N = 8823) were each compared with 1 593 354 newborns of women without a disability. Outcomes were preterm birth <37 and <34 weeks, small for gestational age birth weight (SGA), large for gestational age birth weight, neonatal morbidity, and mortality, neonatal abstinence syndrome (NAS), and NICU admission. Relative risks were adjusted for social, health, and health care characteristics.

RESULTS

Risks for neonatal complications were elevated among newborns of women with disabilities compared with those without disabilities. Adjusted relative risks were especially high for newborns of women with an intellectual or developmental disability, including preterm birth <37 weeks (1.37, 95% confidence interval 1.19-1.58), SGA (1.37, 1.24-1.59), neonatal morbidity (1.42, 1.27-1.60), NAS (1.53, 1.12-2.08), and NICU admission (1.53, 1.40-1.67). The same was seen for newborns of women with ≥2 disabilities, including preterm birth <37 weeks (1.48, 1.39-1.59), SGA (1.13, 1.07-1.20), neonatal morbidity (1.28, 1.20-1.36), NAS (1.87, 1.57-2.23), and NICU admission (1.35, 1.29-1.42).

CONCLUSIONS

There is a mild to moderate elevated risk for complications among newborns of women with disabilities. These women may need adapted and enhanced preconception and prenatal care, and their newborns may require extra support after birth.

摘要

目的

评估残疾女性新生儿并发症的风险。

方法

本基于人群的队列研究纳入了 2003 年至 2018 年加拿大安大略省所有医院单胎活产儿。将患有身体残疾(N=144187)、感官残疾(N=44988)、智力或发育残疾(N=2207)或≥2 种残疾(N=8823)的女性的新生儿分别与 1593354 名无残疾女性的新生儿进行比较。结局为早产<37 周和<34 周、小于胎龄出生体重(SGA)、大于胎龄出生体重、新生儿发病率和死亡率、新生儿戒断综合征(NAS)和新生儿重症监护病房(NICU)入院。相对风险根据社会、健康和医疗保健特征进行调整。

结果

与无残疾女性的新生儿相比,残疾女性的新生儿发生新生儿并发症的风险更高。尤其是智力或发育残疾女性的新生儿,其调整后的相对风险更高,包括早产<37 周(1.37,95%置信区间 1.19-1.58)、SGA(1.37,1.24-1.59)、新生儿发病率(1.42,1.27-1.60)、NAS(1.53,1.12-2.08)和 NICU 入院(1.53,1.40-1.67)。≥2 种残疾女性的新生儿也存在同样情况,包括早产<37 周(1.48,1.39-1.59)、SGA(1.13,1.07-1.20)、新生儿发病率(1.28,1.20-1.36)、NAS(1.87,1.57-2.23)和 NICU 入院(1.35,1.29-1.42)。

结论

残疾女性新生儿发生并发症的风险轻度至中度升高。这些女性可能需要适应性和增强型孕前和产前护理,她们的新生儿出生后可能需要额外的支持。

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