Amini Ryan, Zhang Zijie, Li Jiuxing, Gu Jimmy, Brennan John D, Li Yingfu
Department of Biochemistry and Biomedical Sciences McMaster University 1280 Main Street West Hamilton Ontario L8S 4K1 Canada.
Biointerfaces Institute McMaster University 1280 Main Street West Hamilton Ontario L8S 4K1 Canada.
Anal Sens. 2022 Sep;2(5):e202200035. doi: 10.1002/anse.202200035. Epub 2022 Jun 7.
nucleic acid aptamers armed and ready for our battle against the monstrous SARS-CoV-2 virus. Often thought of as "chemical antibodies", these molecular recognition elements are equipped with several unique benefits and have thus been a popular research subject worldwide. Many aptamers for recognizing the spike and nucleocapsid proteins of SARS-CoV-2 have been developed and examined as diagnostic and therapeutic weaponry for the war against COVID-19 and future pandemics. More information can be found in the Review by J. D. Brennan, Y. Li, and co-workers.
核酸适配体已准备就绪,投身于对抗可怕的SARS-CoV-2病毒的战斗中。这些分子识别元件常被视为“化学抗体”,具备若干独特优势,因而成为全球热门的研究课题。许多用于识别SARS-CoV-2刺突蛋白和核衣壳蛋白的适配体已被开发出来,并作为对抗COVID-19及未来大流行疾病的诊断和治疗武器进行了研究。更多信息可在J. D. Brennan、Y. Li及其同事的综述中找到。