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系统性血压降低对高血压患者眼压的急性影响。

The acute effect of systemic blood pressure reduction on intraocular pressure in hypertensive patients.

作者信息

Tiambeng Canan, Batur Ali, Dikmetas Özlem, Aksu Nalan Metin

机构信息

Department of Emergency Medicine, Faculty of Medicine, Hacettepe University, Altindag, Ankara, Turkey.

Department of Ophthalmology, Faculty of Medicine, Hacettepe University, Altindag, Ankara, Turkey.

出版信息

Turk J Emerg Med. 2022 Jul 1;22(3):131-136. doi: 10.4103/2452-2473.348441. eCollection 2022 Jul-Sep.

DOI:10.4103/2452-2473.348441
PMID:35936951
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9355068/
Abstract

OBJECTIVES

Previous studies have shown an association between systemic hypertension and intraocular pressure (IOP). We analyzed the relationship between the decreases of the blood pressure (BP) and IOP in hypertensive patients.

METHODS

The study includes a total of 214 patients: 158 hypertensive and 56 normotensive patients as study and control groups, respectively. The IOP of each eye in both the groups was measured once with a noncontact tonometer at presentation and an hour after BP reduction to normal in the study group. We analyzed the reduction in IOP with decreasing BP.

RESULTS

In the study group, the mean IOP was 15.29 ± 4.05 mmHg in the right and 15.11 ± 3.78 mmHg in the left eyes. The mean IOP measured an hour after the patients became normotensive was 13.78 ± 4.06 mmHg in the right and 13.51 ± 3.82 in the left eyes. There was a statistically significant decrease in the IOPs ( < 0.001). The mean IOP in the control group was 13.54 ± 3.51 mmHg in the right and 13.20 ± 3.33 mmHg in the left eyes. The mean IOP at presentation in the study and control groups was found to be significantly different ( < 0.001).

CONCLUSIONS

Patients in the study group showed a significantly higher IOP compared to patients in the normotensive group. Furthermore, patients in the study group showed a significant reduction in IOP after BP reduction. This may indicate that uncontrolled hypertension poses a risk for prolonged higher IOP. Prolonged higher IOP can be considered a risk factor for the glaucoma.

摘要

目的

既往研究表明系统性高血压与眼压(IOP)之间存在关联。我们分析了高血压患者血压(BP)降低与眼压降低之间的关系。

方法

该研究共纳入214例患者,分别为158例高血压患者和56例血压正常患者作为研究组和对照组。两组患者每只眼睛在就诊时均使用非接触眼压计测量一次眼压,研究组患者血压降至正常后1小时再次测量。我们分析了随着血压降低眼压的下降情况。

结果

在研究组中,右眼平均眼压为15.29±4.05mmHg,左眼为15.11±3.78mmHg。患者血压恢复正常1小时后测量的平均眼压,右眼为13.78±4.06mmHg,左眼为13.51±3.82mmHg。眼压有统计学显著下降(<0.001)。对照组右眼平均眼压为13.54±3.51mmHg,左眼为13.20±3.33mmHg。研究组和对照组就诊时的平均眼压存在显著差异(<0.001)。

结论

与血压正常组患者相比,研究组患者的眼压显著更高。此外,研究组患者血压降低后眼压显著降低。这可能表明未控制的高血压会导致眼压长期升高的风险。长期眼压升高可被视为青光眼的一个危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8d8/9355068/67afbb256f29/TJEM-22-131-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8d8/9355068/67afbb256f29/TJEM-22-131-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8d8/9355068/67afbb256f29/TJEM-22-131-g001.jpg

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