Bagheri Elmira, Sarraf Shirazi Alireza, Shekofteh Kiana
Department of Pediatric Dentistry, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Dental Biomaterials, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Front Dent. 2022 Feb 8;19:10. doi: 10.18502/fid.v19i10.8855. eCollection 2022.
Incorporation of fillers might improve the physical properties of sealants. This systematic review and meta-analysis evaluated the retention and caries development rate of filled and unfilled fissure sealants. This study was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. The PubMed, Scopus, Embase, Cochrane Database of Systematic Reviews, and ISI Web of Knowledge were searched until October 24, 2019. The risk of bias (ROB) was assessed for the included studies based on the Cochrane collaboration common scheme for bias, and the meta-analysis was performed through a random effects model. The search resulted in 6,336 unrepeated relevant studies. After the title, abstract and full-text screening, 19 studies with 26 comparing groups were finally included in this systematic review and meta-analysis. According to the included studies, both retention rate and caries development in filled and unfilled resin-based sealants did not significantly differ within 2 years of follow-up. Since there was no significant difference in the retention rate and caries development between filled and unfilled sealants, it seems that the final decision should be made uniquely for each patient according to the type of fissure, patient's age, habits, etc.
添加填料可能会改善封闭剂的物理性能。本系统评价和荟萃分析评估了含填料和不含填料的窝沟封闭剂的保留率和龋齿发生率。本研究按照系统评价和荟萃分析的首选报告项目指南进行。检索了截至2019年10月24日的PubMed、Scopus、Embase、Cochrane系统评价数据库和ISI科学网。根据Cochrane协作组的偏倚通用方案对纳入研究的偏倚风险进行评估，并通过随机效应模型进行荟萃分析。检索结果为6336项不重复的相关研究。经过标题、摘要和全文筛选，最终有19项研究、26个比较组纳入本系统评价和荟萃分析。根据纳入研究，含填料和不含填料的树脂基封闭剂在随访2年内的保留率和龋齿发生率均无显著差异。由于含填料和不含填料的封闭剂在保留率和龋齿发生率方面无显著差异，因此似乎应根据窝沟类型、患者年龄、习惯等因素为每个患者做出唯一的最终决定。
