Orum Terese G, Ishola Olayinka O, Adebowale Oluwawemimo O
Department of Veterinary Public Health and Preventive Medicine, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria.
Department of Veterinary Public Health and Preventive Medicine, College of Veterinary Medicine, Federal University of Agriculture, Abeokuta, Ogun State, Nigeria.
Afr J Lab Med. 2022 Jul 20;11(1):1606. doi: 10.4102/ajlm.v11i1.1606. eCollection 2022.
species are among the major foodborne pathogens causing diseases of economic and public health implications in poultry and humans globally.
This study aimed to determine the occurrence and antimicrobial susceptibility patterns of isolates from chickens in poultry farms in Ibadan, Southwest Nigeria.
Cloacal swab samples ( = 360) were obtained from chickens randomly selected from 10 poultry farms in five local government areas of Ibadan, Oyo State, from 04 April 2018 to 20 November 2018. Bacterial identification and antimicrobial susceptibility testing were performed using established protocols. Data were analysed using descriptive statistics and Pearson's chi-squared test at ≤ 0.05 significance level.
The overall prevalence of was 21.4%. There were statistically significant associations between prevalence and the farm location ( = 0.003), age of chickens ( < 0.001), and health status of chickens ( < 0.001). All isolates ( = 77; 100.0%) were resistant to cefuroxime. The isolates were also highly resistant to cotrimoxazole ( = 74; 96.1%), chloramphenicol ( = 73; 94.8%), meropenem ( = 72; 93.5%), gentamicin ( = 69; 89.6%), and tetracycline ( = 64; 83.1%).
The presence of drug-resistant in commercial layer chickens in Ibadan is a potential threat to consumer health as it increases the risk of carcass contamination and pathogen propagation, and limits the options to control and treat infections in humans and animals. Well-integrated national surveillance systems for monitoring and antimicrobial resistance in poultry are critical.
该菌是全球范围内在家禽和人类中引发具有经济和公共卫生影响疾病的主要食源性病原体之一。
本研究旨在确定尼日利亚西南部伊巴丹家禽农场鸡群中该菌的发生情况及抗菌药物敏感性模式。
于2018年4月4日至2018年11月20日，从奥约州伊巴丹五个地方政府区域的10个家禽农场随机选取鸡群，采集泄殖腔拭子样本（n = 360）。使用既定方案进行细菌鉴定和抗菌药物敏感性测试。采用描述性统计和Pearson卡方检验对数据进行分析，显著性水平设定为p≤0.05。
该菌的总体患病率为21.4%。该菌患病率与农场位置（p = 0.003）、鸡的年龄（p < 0.001）以及鸡的健康状况（p < 0.001）之间存在统计学显著关联。所有该菌分离株（n = 77；100.0%）对头孢呋辛耐药。这些分离株对复方新诺明（n = 74；96.1%）、氯霉素（n = 73；94.8%）、美罗培南（n = 72；93.5%）、庆大霉素（n = 69；89.6%）和四环素（n = 64；83.1%）也高度耐药。
伊巴丹商业蛋鸡中存在耐药该菌对消费者健康构成潜在威胁，因为这增加了胴体污染和病原体传播的风险，并限制了控制和治疗人和动物感染的选择。完善整合的国家家禽监测系统对于监测该菌及抗菌药物耐药性至关重要。
