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芦荟漱口水与氯己定对固定正畸患者抗牙菌斑和抗牙龈炎效果的比较——一项随机对照试验

Comparison of antiplaque and anti-gingivitis effects of aloe vera mouthwash with chlorhexidine in fixed orthodontic patients-A randomized controlled trial.

作者信息

Kamath Deepa G, Nadimpalli Harshitha, Nayak Sangeeta Umesh, Rajendran Valliammai, Natarajan Srikant

机构信息

Department of Periodontology, Manipal College of Dental Sciences, Mangalore, Manipal Academy of Higher Education, Manipal, India.

Department of Oral Pathology, Manipal College of Dental Sciences, Mangalore, Manipal Academy of Higher Education, Manipal, India.

出版信息

Int J Dent Hyg. 2023 Feb;21(1):211-218. doi: 10.1111/idh.12615. Epub 2022 Aug 19.

Abstract

BACKGROUND

In daily dental practice, plaque-induced gingivitis is one of the most common periodontal diseases that is frequently encountered. Accumulation of microbial biofilms on surfaces of teeth and poor or inadequate oral hygiene is the chief predisposing factor for this condition. In such a state, antimicrobial mouthwash as an adjunct to mechanical plaque control helps in maintaining good oral hygiene. Among the many conditions, fixed orthodontic treatment is one of the conditions where plaque control becomes challenging to the patient as well as the dentist. In such a situation, antimicrobial mouthwash as an adjunct to mechanical plaque control is highly recommended. Dentistry has recently evidenced a shift of approach for treating many inflammatory oral diseases by using herbal treatment modalities. Aloe vera is one such product exhibiting multiple benefits and has gained considerable importance in clinical research recently. The present study aimed to evaluate efficacy of aloe vera mouth rinse on the dental plaque and gingivitis in patients who were undergoing fixed orthodontic treatment in comparison with 0.2% chlorhexidine mouthwash.

MATERIAL AND METHOD

This randomized controlled trial was conducted on 30 subjects with fixed orthodontic treatment. The subjects were grouped in the test group (15 subjects with 10 ml aloe vera mouthwash (99.6% [w/v])) and the control group (15 subjects with 0.2% 10 ml chlorhexidine mouthwash). Plaque index, gingival index and bleeding on probing were recorded for each participant at baseline, 21 days from baseline and 35 days from baseline. The findings were then statistically analysed using student paired and unpaired t-test.

RESULTS

Gingival index showed a statistically significant difference from baseline to 21 days and 35 days visit in both the groups. Plaque index and bleeding on probing were statistically significant among both groups when compared baseline to 21 days and 35 days visit, but the difference was not significant between visit 2 and visit 3.

CONCLUSIONS

Although chlorhexidine is still the gold standard mouthwash, aloe vera exhibits promising results in reducing plaque and gingivitis scores, without any reported adverse effects. Larger multi-centric trials are needed to prove its effectiveness on dental plaque-induced gingivitis.

摘要

背景

在日常牙科实践中,菌斑性牙龈炎是最常见的牙周疾病之一。牙齿表面微生物生物膜的堆积以及口腔卫生不良或不足是导致这种情况的主要诱发因素。在这种状态下,抗菌漱口水作为机械性菌斑控制的辅助手段有助于保持良好的口腔卫生。在众多情况中,固定正畸治疗是使患者和牙医在菌斑控制方面都面临挑战的情况之一。在这种情况下,强烈推荐使用抗菌漱口水作为机械性菌斑控制的辅助手段。牙科最近已证明通过使用草药治疗方式来治疗许多炎症性口腔疾病的方法发生了转变。芦荟就是这样一种具有多种益处的产品,并且最近在临床研究中已变得相当重要。本研究旨在评估芦荟漱口水与0.2%氯己定漱口水相比,对接受固定正畸治疗的患者的牙菌斑和牙龈炎的疗效。

材料与方法

本随机对照试验对30名接受固定正畸治疗的受试者进行。受试者被分为试验组(15名受试者使用10毫升芦荟漱口水(99.6%[w/v]))和对照组(15名受试者使用0.2%的1O毫升氯己定漱口水)。在基线、基线后21天和基线后35天为每位参与者记录菌斑指数、牙龈指数和探诊出血情况。然后使用学生配对和非配对t检验对结果进行统计学分析。

结果

两组从基线到21天和35天复诊时牙龈指数均显示出统计学上的显著差异。与基线相比,两组在21天和35天复诊时菌斑指数和探诊出血在统计学上具有显著差异,但在第2次和第3次复诊之间差异不显著。

结论

尽管氯己定仍然是漱口水的金标准,但芦荟在降低菌斑和牙龈炎评分方面显示出有希望的结果,且未报告任何不良反应。需要更大规模的多中心试验来证明其对菌斑性牙龈炎的有效性。

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